{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T09:10:39Z","timestamp":1786612239081,"version":"build-2736575974"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The application of emerging metabolomics technologies to the comprehensive investigation of cellular biochemistry has been limited by bottlenecks in data processing, particularly noise filtering and metabolite identification. IDEOM provides a user-friendly data processing application that automates filtering and identification of metabolite peaks, paying particular attention to common sources of noise and false identifications generated by liquid chromatography\u2013mass spectrometry (LC\u2013MS) platforms. Building on advanced processing tools such as mzMatch and XCMS, it allows users to run a comprehensive pipeline for data analysis and visualization from a graphical user interface within Microsoft Excel, a familiar program for most biological scientists.<\/jats:p>\n               <jats:p>Availability and implementation: IDEOM is provided free of charge at http:\/\/mzmatch.sourceforge.net\/ideom.html, as a macro-enabled spreadsheet (.xlsb). Implementation requires Microsoft Excel (2007 or later). R is also required for full functionality.<\/jats:p>\n               <jats:p>Contact: \u00a0michael.barrett@glasgow.ac.uk<\/jats:p>\n               <jats:p>Supplementary Information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts069","type":"journal-article","created":{"date-parts":[[2012,2,5]],"date-time":"2012-02-05T01:43:47Z","timestamp":1328406227000},"page":"1048-1049","source":"Crossref","is-referenced-by-count":317,"title":["IDEOM: an Excel interface for analysis of LC\u2013MS-based metabolomics data"],"prefix":"10.1093","volume":"28","author":[{"given":"Darren J.","family":"Creek","sequence":"first","affiliation":[{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"},{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andris","family":"Jankevics","sequence":"additional","affiliation":[{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"},{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl E. V.","family":"Burgess","sequence":"additional","affiliation":[{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Breitling","sequence":"additional","affiliation":[{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"},{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Barrett","sequence":"additional","affiliation":[{"name":"1 Institute of Infection, Immunity and Inflammation, Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK, 2Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia, 3Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK and 4Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 CC Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,2,4]]},"reference":[{"key":"2023012512220803000_B1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s11306-010-0270-3","article-title":"Bioinformatics tools for cancer metabolomics","volume":"7","author":"Blekherman","year":"2011","journal-title":"Metabolomics"},{"key":"2023012512220803000_B2","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.tibtech.2006.10.006","article-title":"Precision mapping of the metabolome","volume":"24","author":"Breitling","year":"2006","journal-title":"Trends Biotech."},{"key":"2023012512220803000_B3","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/bioinformatics\/btr079","article-title":"Automated workflows for accurate mass-based putative metabolite identification in LC\/MS-derived metabolomic datasets","volume":"27","author":"Brown","year":"2011","journal-title":"Bioinformatics"},{"key":"2023012512220803000_B4","doi-asserted-by":"crossref","first-page":"8703","DOI":"10.1021\/ac2021823","article-title":"Towards global metabolomics analysis with Liquid Chromatography-Mass Spectrometry: improved metabolite identification by retention time prediction","volume":"83","author":"Creek","year":"2011","journal-title":"Anal. 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