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We demonstrate that commonly used positive and negative controls may be unreliable and provide a rational methodology with which to replace them.<\/jats:p>\n               <jats:p>Contact: \u00a0w.ritchie@centenary.org.au<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts114","type":"journal-article","created":{"date-parts":[[2012,3,10]],"date-time":"2012-03-10T01:39:55Z","timestamp":1331343595000},"page":"1058-1061","source":"Crossref","is-referenced-by-count":24,"title":["Defining and providing robust controls for microRNA prediction"],"prefix":"10.1093","volume":"28","author":[{"given":"William","family":"Ritchie","sequence":"first","affiliation":[]},{"given":"Dadi","family":"Gao","sequence":"additional","affiliation":[]},{"given":"John E. 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