{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:35:41Z","timestamp":1776321341264,"version":"3.50.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Anuran tissues, and especially skin, are a rich source of bioactive peptides and their precursors. We here present a manually curated database of antimicrobial and other defense peptides with a total of 2571 entries, most of them in the precursor form with demarcated signal peptide (SP), acidic proregion(s) and bioactive moiety(s) corresponding to 1923 non-identical bioactive sequences. Search functions on the corresponding web server facilitate the extraction of six distinct SP classes. The more conserved of these can be used for searching cDNA and UniProtKB databases for potential bioactive peptides, for creating PROSITE search patterns, and for phylogenetic analysis.<\/jats:p>\n               <jats:p>Availability: DADP is accessible at http:\/\/split4.pmfst.hr\/dadp\/<\/jats:p>\n               <jats:p>Contact: \u00a0juretic@pmfst.hr<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts141","type":"journal-article","created":{"date-parts":[[2012,3,31]],"date-time":"2012-03-31T00:24:47Z","timestamp":1333153487000},"page":"1406-1407","source":"Crossref","is-referenced-by-count":198,"title":["DADP: the database of anuran defense peptides"],"prefix":"10.1093","volume":"28","author":[{"given":"Mario","family":"Novkovi\u0107","sequence":"first","affiliation":[{"name":"1 Department of Physics, Faculty of Science, University of Split, 21000 Split, 2Centre for Informatics and Computing, Ru\u0111er Bo\u0161kovi\u0107 Institute, 10000 Zagreb, Croatia and 3Department of Life Sciences, University of Trieste, 34127 Trieste, Italy"}]},{"given":"Juraj","family":"Simuni\u0107","sequence":"additional","affiliation":[{"name":"1 Department of Physics, Faculty of Science, University of Split, 21000 Split, 2Centre for Informatics and Computing, Ru\u0111er Bo\u0161kovi\u0107 Institute, 10000 Zagreb, Croatia and 3Department of Life Sciences, University of Trieste, 34127 Trieste, Italy"}]},{"given":"Viktor","family":"Bojovi\u0107","sequence":"additional","affiliation":[{"name":"1 Department of Physics, Faculty of Science, University of Split, 21000 Split, 2Centre for Informatics and Computing, Ru\u0111er Bo\u0161kovi\u0107 Institute, 10000 Zagreb, Croatia and 3Department of Life Sciences, University of Trieste, 34127 Trieste, Italy"}]},{"given":"Alessandro","family":"Tossi","sequence":"additional","affiliation":[{"name":"1 Department of Physics, Faculty of Science, University of Split, 21000 Split, 2Centre for Informatics and Computing, Ru\u0111er Bo\u0161kovi\u0107 Institute, 10000 Zagreb, Croatia and 3Department of Life Sciences, University of Trieste, 34127 Trieste, Italy"}]},{"given":"Davor","family":"Jureti\u0107","sequence":"additional","affiliation":[{"name":"1 Department of Physics, Faculty of Science, University of Split, 21000 Split, 2Centre for Informatics and Computing, Ru\u0111er Bo\u0161kovi\u0107 Institute, 10000 Zagreb, Croatia and 3Department of Life Sciences, University of Trieste, 34127 Trieste, Italy"}]}],"member":"286","published-online":{"date-parts":[[2012,3,29]]},"reference":[{"key":"2023012512303110000_B1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1093\/nar\/gkq1020","article-title":"Ongoing and future developments at the Universal Protein Resource","volume":"39","author":"Apweiler","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"2023012512303110000_B2","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2004.05.028","article-title":"Improved prediction of signal peptides: SignalP 3.0","volume":"340","author":"Bendtsen","year":"2004","journal-title":"J. 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