{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T09:41:26Z","timestamp":1725615686841},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":1623,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic.<\/jats:p>\n               <jats:p>Availability and implementation: The tool is publicly accessible as a webserver at http:\/\/tachyon.bii.a-star.edu.sg and can also be accessed programmatically through SOAP.<\/jats:p>\n               <jats:p>Contact: \u00a0sebastianms@bii.a-star.edu.sg<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at the Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts197","type":"journal-article","created":{"date-parts":[[2012,4,25]],"date-time":"2012-04-25T00:58:05Z","timestamp":1335315485000},"page":"1645-1646","source":"Crossref","is-referenced-by-count":12,"title":["Tachyon search speeds up retrieval of similar sequences by several orders of magnitude"],"prefix":"10.1093","volume":"28","author":[{"given":"Joshua","family":"Tan","sequence":"first","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"},{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Durga","family":"Kuchibhatla","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Fernanda L.","family":"Sirota","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Westley A.","family":"Sherman","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Tobias","family":"Gattermayer","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Chia Yee","family":"Kwoh","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Frank","family":"Eisenhaber","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"},{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"},{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Georg","family":"Schneider","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 117597, 4School of Computer Engineering (SCE), Nanyang Technological University (NTU), 50 Nanyang Drive, 637553 and 5School of Biological Sciences (SBS), Nanyang Technological University (NTU), 60 Nanyang Drive, 637551, Singapore"}]},{"given":"Sebastian","family":"Maurer-Stroh","sequence":"additional","affiliation":[{"name":"1 Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, 2Institute of High Performance Computing (IHPC), Agency for Science Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16 Connexis, 138632, 3Department of Biological Sciences (DBS), National University of Singapore (NUS), 8 Medical Drive 4, 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