{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:29:09Z","timestamp":1772159349135,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Many drug discovery projects fail because the underlying target is finally found to be undruggable. Progress in structure elucidation of proteins now opens up a route to automatic structure-based target assessment. DoGSiteScorer is a newly developed automatic tool combining pocket prediction, characterization and druggability estimation and is now available through a web server.<\/jats:p>\n               <jats:p>Availability: The DoGSiteScorer web server is freely available for academic use at http:\/\/dogsite.zbh.uni-hamburg.de<\/jats:p>\n               <jats:p>Contact: \u00a0rarey@zbh.uni-hamburg.de.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts310","type":"journal-article","created":{"date-parts":[[2012,5,25]],"date-time":"2012-05-25T01:19:20Z","timestamp":1337908760000},"page":"2074-2075","source":"Crossref","is-referenced-by-count":505,"title":["DoGSiteScorer: a web server for automatic binding site prediction, analysis and druggability assessment"],"prefix":"10.1093","volume":"28","author":[{"given":"Andrea","family":"Volkamer","sequence":"first","affiliation":[{"name":"1 Center for Bioinformatics, University of Hamburg, Bundesstr and 2Merck KGaA, Merck Serono, Global Computational Chemistry, Frankfurter Str. 250, 64293 Darmstadt, Germany"}]},{"given":"Daniel","family":"Kuhn","sequence":"additional","affiliation":[{"name":"1 Center for Bioinformatics, University of Hamburg, Bundesstr and 2Merck KGaA, Merck Serono, Global Computational Chemistry, Frankfurter Str. 250, 64293 Darmstadt, Germany"}]},{"given":"Friedrich","family":"Rippmann","sequence":"additional","affiliation":[{"name":"1 Center for Bioinformatics, University of Hamburg, Bundesstr and 2Merck KGaA, Merck Serono, Global Computational Chemistry, Frankfurter Str. 250, 64293 Darmstadt, Germany"}]},{"given":"Matthias","family":"Rarey","sequence":"additional","affiliation":[{"name":"1 Center for Bioinformatics, University of Hamburg, Bundesstr and 2Merck KGaA, Merck Serono, Global Computational Chemistry, Frankfurter Str. 250, 64293 Darmstadt, Germany"}]}],"member":"286","published-online":{"date-parts":[[2012,5,23]]},"reference":[{"key":"2023012512452688700_B1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1073\/pnas.0707684105","article-title":"A threading-based method (findsite) for ligand-binding site prediction and functional annotation","volume":"105","author":"Brylinski","year":"2008","journal-title":"Proc. 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