{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T03:51:21Z","timestamp":1773892281190,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The R\/Bioconductor package HiTC facilitates the exploration of high-throughput 3C-based data. It allows users to import and export \u2018C\u2019 data, to transform, normalize, annotate and visualize interaction maps. The package operates within the Bioconductor framework and thus offers new opportunities for future development in this field.<\/jats:p>\n               <jats:p>Availability and implementation: The R package HiTC is available from the Bioconductor website. A detailed vignette provides additional documentation and help for using the package.<\/jats:p>\n               <jats:p>Contact: \u00a0nicolas.servant@curie.fr<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts521","type":"journal-article","created":{"date-parts":[[2012,8,25]],"date-time":"2012-08-25T02:27:06Z","timestamp":1345861626000},"page":"2843-2844","source":"Crossref","is-referenced-by-count":191,"title":["HiTC: exploration of high-throughput \u2018C\u2019 experiments"],"prefix":"10.1093","volume":"28","author":[{"given":"Nicolas","family":"Servant","sequence":"first","affiliation":[{"name":"1 Institut Curie, F-75248 Paris, France, 2INSERM, U900, F-75248 Paris, France, 3Ecole des Mines ParisTech, F-77300 Fontainebleau, France, 4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA, 5CNRS UMR3215, F-75248 Paris, France and 6INSERM U934, F-75248 Paris, France"},{"name":"1 Institut Curie, F-75248 Paris, France, 2INSERM, U900, F-75248 Paris, France, 3Ecole des Mines ParisTech, F-77300 Fontainebleau, France, 4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA, 5CNRS UMR3215, F-75248 Paris, France and 6INSERM U934, F-75248 Paris, France"},{"name":"1 Institut Curie, F-75248 Paris, France, 2INSERM, U900, F-75248 Paris, France, 3Ecole des Mines ParisTech, F-77300 Fontainebleau, France, 4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA, 5CNRS UMR3215, F-75248 Paris, France and 6INSERM U934, F-75248 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan R.","family":"Lajoie","sequence":"additional","affiliation":[{"name":"1 Institut Curie, F-75248 Paris, France, 2INSERM, U900, F-75248 Paris, France, 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