{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:08:22Z","timestamp":1771463302113,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Cancer is the leading cause of death worldwide. Screening anticancer candidates from tens of millions of chemical compounds is expensive and time-consuming. A rapid and user-friendly web server, known as CDRUG, is described here to predict the anticancer activity of chemical compounds. In CDRUG, a hybrid score was developed to measure the similarity of different compounds. The performance analysis shows that CDRUG has the area under curve of 0.878, indicating that CDRUG is effective to distinguish active and inactive compounds.<\/jats:p>\n               <jats:p>Availability: The CDRUG web server and the standard-alone version are freely available at http:\/\/bsb.kiz.ac.cn\/CDRUG\/.<\/jats:p>\n               <jats:p>Contact: \u00a0huangjf@mail.kiz.ac.cn<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts625","type":"journal-article","created":{"date-parts":[[2012,10,19]],"date-time":"2012-10-19T01:31:14Z","timestamp":1350610274000},"page":"3334-3335","source":"Crossref","is-referenced-by-count":47,"title":["CDRUG: a web server for predicting anticancer activity of chemical compounds"],"prefix":"10.1093","volume":"28","author":[{"given":"Gong-Hua","family":"Li","sequence":"first","affiliation":[{"name":"1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences and 2Kunming Institute of Zoology-Chinese University of Hongkong Joint Research Center for Bio-resources and Human Disease Mechanisms, Kunming, Yunnan 650223, China"}]},{"given":"Jing-Fei","family":"Huang","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences and 2Kunming Institute of Zoology-Chinese University of Hongkong Joint Research Center for Bio-resources and Human Disease Mechanisms, Kunming, Yunnan 650223, China"},{"name":"1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences and 2Kunming Institute of Zoology-Chinese University of Hongkong Joint Research Center for Bio-resources and Human Disease Mechanisms, Kunming, Yunnan 650223, China"}]}],"member":"286","published-online":{"date-parts":[[2012,10,18]]},"reference":[{"key":"2023012513244471500_bts625-B1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nrc1529","article-title":"Timeline\u2014chemotherapy and the war on cancer","volume":"5","author":"Chabner","year":"2005","journal-title":"Nat Rev. 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