{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:53:21Z","timestamp":1770598401449,"version":"3.49.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: ENSEMBLE is a computational approach for determining a set of conformations that represents the structural ensemble of a disordered protein based on input experimental data. The disordered protein can be an unfolded or intrinsically disordered state. Here, we introduce the latest version of the program, which has been enhanced to facilitate its general release and includes an intuitive user interface, as well as new approaches to treat data and analyse results.<\/jats:p>\n               <jats:p>Availability and implementation: ENSEMBLE is a program implemented in C and embedded in a Perl wrapper. It is supported on main Linux distributions. Source codes and installation files, including a detailed example, can be freely downloaded at http:\/\/abragam.med.utoronto.ca\/\u223cJFKlab.<\/jats:p>\n               <jats:p>Contact: forman@sickkids.ca<\/jats:p>\n               <jats:p>Supplementary information: Supplementary Material are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/bts701","type":"journal-article","created":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T03:06:16Z","timestamp":1355281576000},"page":"398-399","source":"Crossref","is-referenced-by-count":140,"title":["Characterization of disordered proteins with ENSEMBLE"],"prefix":"10.1093","volume":"29","author":[{"given":"Micka\u00ebl","family":"Krzeminski","sequence":"first","affiliation":[{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"}]},{"given":"Joseph A.","family":"Marsh","sequence":"additional","affiliation":[{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"},{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"}]},{"given":"Chris","family":"Neale","sequence":"additional","affiliation":[{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"},{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"}]},{"given":"Wing-Yiu","family":"Choy","sequence":"additional","affiliation":[{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"},{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"}]},{"given":"Julie D.","family":"Forman-Kay","sequence":"additional","affiliation":[{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"},{"name":"1 Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada and 2Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada"}]}],"member":"286","published-online":{"date-parts":[[2012,12,11]]},"reference":[{"key":"2023012810214529100_bts701-B1","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1107\/S0907444998003254","article-title":"Crystallography & NMR system: a new software suite for macromolecular structure determination","volume":"54","author":"Brunger","year":"1998","journal-title":"Acta. 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