{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T12:48:59Z","timestamp":1776257339084,"version":"3.50.1"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":1311,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: Retrocopies are copies of mature RNAs that are usually devoid of regulatory sequences and introns. They have routinely been classified as processed pseudo-genes with little or no biological relevance. However, recent findings have revealed functional roles for retrocopies, as well as their high frequency in some organisms, such as primates. Despite their increasing importance, there is no user-friendly and publicly available resource for the study of retrocopies.<\/jats:p>\n               <jats:p>Results: Here, we present RCPedia, an integrative and user-friendly database designed for the study of retrocopied genes. RCPedia contains a complete catalogue of the retrocopies that are known to be present in human and five other primate genomes, their genomic context, inter-species conservation and gene expression data. RCPedia also offers a streamlined data representation and an efficient query system.<\/jats:p>\n               <jats:p>Availability and implementation: RCPedia is available at http:\/\/www.bioinfo.mochsl.org.br\/rcpedia.<\/jats:p>\n               <jats:p>Contact: \u00a0pgalante@mochsl.org.br<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btt104","type":"journal-article","created":{"date-parts":[[2013,3,2]],"date-time":"2013-03-02T10:23:13Z","timestamp":1362219793000},"page":"1235-1237","source":"Crossref","is-referenced-by-count":33,"title":["RCPedia: a database of retrocopied genes"],"prefix":"10.1093","volume":"29","author":[{"given":"F\u00e1bio C. P.","family":"Navarro","sequence":"first","affiliation":[{"name":"1 Centro de Oncologia Molecular, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo 01308-060, Brazil and 2Departmento de Bioqu\u00edmica, Universidade de S\u00e3o Paulo, S\u00e3o Paulo 05508-000, Brazil"},{"name":"1 Centro de Oncologia Molecular, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo 01308-060, Brazil and 2Departmento de Bioqu\u00edmica, Universidade de S\u00e3o Paulo, S\u00e3o Paulo 05508-000, Brazil"}]},{"given":"Pedro A. F.","family":"Galante","sequence":"additional","affiliation":[{"name":"1 Centro de Oncologia Molecular, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo 01308-060, Brazil and 2Departmento de Bioqu\u00edmica, Universidade de S\u00e3o Paulo, S\u00e3o Paulo 05508-000, Brazil"}]}],"member":"286","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"key":"2023012810383563400_btt104-B1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/nature10532","article-title":"The evolution of gene expression levels in mammalian organs","volume":"478","author":"Brawand","year":"2011","journal-title":"Nature"},{"key":"2023012810383563400_btt104-B2","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/molbev\/mss235","article-title":"\u201cOrphan\u201d retrogenes in the human genome","volume":"30","author":"Ciomborowska","year":"2013","journal-title":"Mol. Biol. 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Genet."},{"key":"2023012810383563400_btt104-B12","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/bioinformatics\/btq057","article-title":"Fast and SNP-tolerant detection of complex variants and splicing in short reads","volume":"26","author":"Wu","year":"2010","journal-title":"Bioinformatics"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/29\/9\/1235\/48899220\/bioinformatics_29_9_1235.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/29\/9\/1235\/48899220\/bioinformatics_29_9_1235.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T12:22:35Z","timestamp":1674908555000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/29\/9\/1235\/218124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,1]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btt104","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2013,5,1]]},"published":{"date-parts":[[2013,3,1]]}}}