{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T06:45:10Z","timestamp":1773297910347,"version":"3.50.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"13","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":1237,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Genome-wide expression analysis can result in large numbers of clusters of co-expressed genes. Although there are tools for ab initio discovery of transcription factor-binding sites, most do not provide a quick and easy way to study large numbers of clusters. To address this, we introduce a web tool called MEME-LaB. The tool wraps MEME (an ab initio motif finder), providing an interface for users to input multiple gene clusters, retrieve promoter sequences, run motif finding and then easily browse and condense the results, facilitating better interpretation of the results from large-scale datasets.<\/jats:p>\n               <jats:p>Availability: MEME-LaB is freely accessible at: http:\/\/wsbc.warwick.ac.uk\/wsbcToolsWebpage\/.<\/jats:p>\n               <jats:p>Contact: \u00a0p.e.brown@warwick.ac.uk<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btt248","type":"journal-article","created":{"date-parts":[[2013,5,17]],"date-time":"2013-05-17T00:30:13Z","timestamp":1368750613000},"page":"1696-1697","source":"Crossref","is-referenced-by-count":65,"title":["MEME-LaB: motif analysis in clusters"],"prefix":"10.1093","volume":"29","author":[{"given":"Paul","family":"Brown","sequence":"first","affiliation":[]},{"given":"Laura","family":"Baxter","sequence":"additional","affiliation":[]},{"given":"Richard","family":"Hickman","sequence":"additional","affiliation":[]},{"given":"Jim","family":"Beynon","sequence":"additional","affiliation":[]},{"given":"Jonathan D.","family":"Moore","sequence":"additional","affiliation":[]},{"given":"Sascha","family":"Ott","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2013,5,14]]},"reference":[{"key":"2023062614233112300_btt248-B1","doi-asserted-by":"crossref","first-page":"W369","DOI":"10.1093\/nar\/gkl198","article-title":"MEME: discovering and analyzing DNA and protein sequence motifs","volume":"34","author":"Bailey","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"2023062614233112300_btt248-B2","doi-asserted-by":"crossref","first-page":"D102","DOI":"10.1093\/nar\/gkm955","article-title":"JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update","volume":"36","author":"Bryne","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"2023062614233112300_btt248-B3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/nar\/27.1.297","article-title":"Plant cis-acting regulatory DNA elements (PLACE) database: 1999","volume":"27","author":"Higo","year":"1999","journal-title":"Nucleic Acids Res."},{"key":"2023062614233112300_btt248-B4","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/bioinformatics\/btr189","article-title":"MEME-ChIP: motif analysis of large DNA datasets","volume":"27","author":"Machanick","year":"2012","journal-title":"Bioinformatics"},{"key":"2023062614233112300_btt248-B5","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.1093\/bioinformatics\/bti714","article-title":"Athena: a resource for rapid visualization and systematic analysis of Arabidopsis promoter sequences","volume":"21","author":"O\u2019Connor","year":"2005","journal-title":"Bioinformatics"},{"key":"2023062614233112300_btt248-B6","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.1105\/tpc.112.102046","article-title":"Arabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis","volume":"24","author":"Windram","year":"2012","journal-title":"Plant Cell"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/29\/13\/1696\/50702708\/bioinformatics_29_13_1696.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/29\/13\/1696\/50702708\/bioinformatics_29_13_1696.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T15:23:38Z","timestamp":1687793018000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/29\/13\/1696\/200209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,14]]},"references-count":6,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2013,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btt248","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2013,7]]},"published":{"date-parts":[[2013,5,14]]}}}