{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T17:15:27Z","timestamp":1782580527278,"version":"3.54.5"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Studies of the human microbiome, and microbial community ecology in general, have blossomed of late and are now a burgeoning source of exciting research findings. Along with the advent of next-generation sequencing platforms, which have dramatically increased the scope of microbiome-related projects, several high-performance sequence analysis pipelines (e.g. QIIME, MOTHUR, VAMPS) are now available to investigators for microbiome analysis. The subject of our manuscript, the graphical user interface-based Explicet software package, fills a previously unmet need for a robust, yet intuitive means of integrating the outputs of the software pipelines with user-specified metadata and then visualizing the combined data.<\/jats:p>\n               <jats:p>Availability and Implementation: Explicet is implemented in C++ via the Qt framework and supported in native code on all major operating systems (Windows, Macintosh, Linux). The source code, documents and tutorials are freely available under an open-source license at www.explicet.org.<\/jats:p>\n               <jats:p>Contact: \u00a0daniel.frank@ucdenver.edu<\/jats:p>","DOI":"10.1093\/bioinformatics\/btt526","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T09:53:20Z","timestamp":1378893200000},"page":"3100-3101","source":"Crossref","is-referenced-by-count":252,"title":["Explicet: graphical user interface software for metadata-driven management, analysis and visualization of microbiome data"],"prefix":"10.1093","volume":"29","author":[{"given":"Charles E.","family":"Robertson","sequence":"first","affiliation":[{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"},{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Kirk","family":"Harris","sequence":"additional","affiliation":[{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"},{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandie D.","family":"Wagner","sequence":"additional","affiliation":[{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"},{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and 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Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA and 6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Tatem","sequence":"additional","affiliation":[{"name":"1 Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA, 2University of Colorado Microbiome Research Consortium, 3Department of Pediatrics, University of Colorado Anschutz Medical Campus, 4Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO 80045, USA, 5Incubix Incorporated, Boulder, CO 80301, USA 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