{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:52:18Z","timestamp":1781207538492,"version":"3.54.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: \u00a0VariantAnnotation is an R \/ Bioconductor package for the exploration and annotation of genetic variants. Capabilities exist for reading, writing and filtering variant call format (VCF) files. VariantAnnotation allows ready access to additional R \/ Bioconductor facilities for advanced statistical analysis, data transformation, visualization and integration with diverse genomic resources.<\/jats:p>\n               <jats:p>Availability and implementation: This package is implemented in R and available for download at the Bioconductor Web site ( http:\/\/bioconductor.org\/packages\/2.13\/bioc\/html\/ VariantAnnotation .html ). The package contains extensive help pages for individual functions and a \u2018vignette\u2019 outlining typical work flows; it is made available under the open source \u2018Artistic-2.0\u2019 license. Version 1.9.38 was used in this article.<\/jats:p>\n               <jats:p>Contact: \u00a0vobencha@fhcrc.org<\/jats:p>","DOI":"10.1093\/bioinformatics\/btu168","type":"journal-article","created":{"date-parts":[[2014,3,29]],"date-time":"2014-03-29T01:45:49Z","timestamp":1396057549000},"page":"2076-2078","source":"Crossref","is-referenced-by-count":353,"title":["<tt>VariantAnnotation<\/tt>\n            : a \n            <tt>Bioconductor<\/tt>\n             package for exploration and annotation of genetic variants"],"prefix":"10.1093","volume":"30","author":[{"given":"Valerie","family":"Obenchain","sequence":"first","affiliation":[{"name":"1 Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, 2 Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, 3 Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, MA 02115 and 4 Department of Biostatistics, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lawrence","sequence":"additional","affiliation":[{"name":"1 Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, 2 Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, 3 Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, MA 02115 and 4 Department of Biostatistics, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Carey","sequence":"additional","affiliation":[{"name":"1 Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, 2 Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, 3 Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, MA 02115 and 4 Department of Biostatistics, University of Washington, Seattle, WA 98195, 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