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RAREMETAL facilitates analyses of individual studies, accommodates a variety of input file formats, handles related and unrelated individuals, executes both single variant and burden tests and performs conditional association analyses.<\/jats:p><jats:p>Availability and implementation: \u00a0http:\/\/genome.sph.umich.edu\/wiki\/RAREMETAL for executables, source code, documentation and tutorial.<\/jats:p><jats:p>Contact: \u00a0sfengsph@umich.edu or goncalo@umich.edu<\/jats:p>","DOI":"10.1093\/bioinformatics\/btu367","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T05:56:45Z","timestamp":1401861405000},"page":"2828-2829","source":"Crossref","is-referenced-by-count":106,"title":["RAREMETAL: fast and powerful meta-analysis for rare variants"],"prefix":"10.1093","volume":"30","author":[{"given":"Shuang","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dajiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Kate","family":"Wing","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gon\u00e7alo R.","family":"Abecasis","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,6,3]]},"reference":[{"key":"2023041303472242400_","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/ng786","article-title":"Merlin\u2014rapid analysis of dense genetic maps using sparse gene flow trees","volume":"30","author":"Abecasis","year":"2002","journal-title":"Nat. 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