{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:18:06Z","timestamp":1760955486279},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Protein interaction network-based pathway analysis (PINBPA) for genome-wide association studies (GWAS) has been developed as a Cytoscape app, to enable analysis of GWAS data in a network fashion. Users can easily import GWAS summary-level data, draw Manhattan plots, define blocks, prioritize genes with random walk with restart, detect enriched subnetworks and test the significance of subnetworks via a user-friendly interface.<\/jats:p>\n               <jats:p>Availability and implementation: PINBPA app is freely available in Cytoscape app store.<\/jats:p>\n               <jats:p>Contact: \u00a0pmousavi@cs.queensu.ca and sebaran@cgl.ucsf.edu<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btu644","type":"journal-article","created":{"date-parts":[[2014,9,27]],"date-time":"2014-09-27T03:04:09Z","timestamp":1411787049000},"page":"262-264","source":"Crossref","is-referenced-by-count":26,"title":["PINBPA: Cytoscape app for network analysis of GWAS data"],"prefix":"10.1093","volume":"31","author":[{"given":"Lili","family":"Wang","sequence":"first","affiliation":[{"name":"1 School of Computing, Queen\u2019s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and 2 Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Matsushita","sequence":"additional","affiliation":[{"name":"1 School of Computing, Queen\u2019s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and 2 Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lohith","family":"Madireddy","sequence":"additional","affiliation":[{"name":"1 School of Computing, Queen\u2019s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and 2 Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parvin","family":"Mousavi","sequence":"additional","affiliation":[{"name":"1 School of Computing, Queen\u2019s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and 2 Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio E.","family":"Baranzini","sequence":"additional","affiliation":[{"name":"1 School of Computing, Queen\u2019s University, 25 Union Street, Goodwin Hall, Kingston, Ontario K7L 3N6, Canada and 2 Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Room 215, San Francisco, CA 94158, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"key":"2023020116154604500_btu644-B1","doi-asserted-by":"crossref","first-page":"E24220","DOI":"10.1371\/journal.pone.0024220","article-title":"A network-based approach to prioritize results from genome-wide association studies","volume":"6","author":"Akula","year":"2011","journal-title":"PLoS One"},{"key":"2023020116154604500_btu644-B2","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/hmg\/ddp120","article-title":"Pathway and network-based analysis of genome-wide association studies in multiple sclerosis","volume":"18","author":"Baranzini","year":"2009","journal-title":"Hum. 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