{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:56:55Z","timestamp":1767830215107,"version":"3.49.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"13","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":591,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Oasis is a web application that allows for the fast and flexible online analysis of small-RNA-seq (sRNA-seq) data. It was designed for the end user in the lab, providing an easy-to-use web frontend including video tutorials, demo data and best practice step-by-step guidelines on how to analyze sRNA-seq data. Oasis\u2019 exclusive selling points are a differential expression module that allows for the multivariate analysis of samples, a classification module for robust biomarker detection and an advanced programming interface that supports the batch submission of jobs. Both modules include the analysis of novel miRNAs, miRNA targets and functional analyses including GO and pathway enrichment. Oasis generates downloadable interactive web reports for easy visualization, exploration and analysis of data on a local system. Finally, Oasis\u2019 modular workflow enables for the rapid (re-) analysis of data.<\/jats:p>\n               <jats:p>Availability and implementation: Oasis is implemented in Python, R, Java, PHP, C++ and JavaScript. It is freely available at http:\/\/oasis.dzne.de.<\/jats:p>\n               <jats:p>Contact: \u00a0stefan.bonn@dzne.de<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv113","type":"journal-article","created":{"date-parts":[[2015,2,21]],"date-time":"2015-02-21T15:10:09Z","timestamp":1424531409000},"page":"2205-2207","source":"Crossref","is-referenced-by-count":56,"title":["Oasis: online analysis of small RNA deep sequencing data"],"prefix":"10.1093","volume":"31","author":[{"given":"Vincenzo","family":"Capece","sequence":"first","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio C.","family":"Garcia Vizcaino","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"},{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramon","family":"Vidal","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raza-Ur","family":"Rahman","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tonatiuh","family":"Pena Centeno","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orr","family":"Shomroni","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irantzu","family":"Suberviola","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Fischer","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Bonn","sequence":"additional","affiliation":[{"name":"1 Laboratory of Computational Systems Biology and 2Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,2,19]]},"reference":[{"key":"2023020202144716100_btv113-B1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random Forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach. 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