{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T06:39:08Z","timestamp":1773211148461,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"16","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":535,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Specific recognition of DNA by proteins is a crucial step of many biological processes. PDIviz is a plugin for the PyMOL molecular visualization system that analyzes protein\u2013DNA binding interfaces by comparing the solvent accessible surface area of the complex against the free protein and free DNA. The plugin provides three distinct three-dimensional visualization modes to highlight interactions with DNA bases and backbone, major and minor groove, and with atoms of different pharmacophoric type (hydrogen bond donors\/acceptors, hydrophobic and thymine methyl). Each mode comes in three styles to focus the visual analysis on the protein or DNA side of the interface, or on the nucleotide sequence. PDIviz allows for the generation of publication quality images, all calculated data can be written to disk, and a command line interface is provided for automating tasks. The plugin may be helpful for the detailed identification of regions involved in DNA base and shape readout, and can be particularly useful in rapidly pinpointing the overall mode of interaction.<\/jats:p>\n               <jats:p>Availability and implementation: Freely available at http:\/\/melolab.org\/pdiviz\/ as a PyMOL plugin. Tested with incentive, educational, and open source versions of PyMOL on Windows, Mac and Linux systems.<\/jats:p>\n               <jats:p>Contact: \u00a0aschueller@bio.puc.cl<\/jats:p>\n               <jats:p>Supplementary Information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv203","type":"journal-article","created":{"date-parts":[[2015,4,18]],"date-time":"2015-04-18T00:21:53Z","timestamp":1429316513000},"page":"2751-2753","source":"Crossref","is-referenced-by-count":19,"title":["PDIviz: analysis and visualization of protein\u2013DNA binding interfaces"],"prefix":"10.1093","volume":"31","author":[{"given":"Judemir","family":"Ribeiro","sequence":"first","affiliation":[{"name":"Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Melo","sequence":"additional","affiliation":[{"name":"Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Sch\u00fcller","sequence":"additional","affiliation":[{"name":"Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,4,16]]},"reference":[{"key":"2023020202215436200_btv203-B1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/nar\/28.1.235","article-title":"The Protein Data Bank","volume":"28","author":"Berman","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"2023020202215436200_btv203-B2","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/254304a0","article-title":"Structural invariants in protein folding","volume":"254","author":"Chothia","year":"1975","journal-title":"Nature"},{"key":"2023020202215436200_btv203-B3","author":"Hubbard","year":"1993"},{"key":"2023020202215436200_btv203-B4","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1186\/1471-2105-11-262","article-title":"The Protein\u2013DNA Interface database","volume":"11","author":"Norambuena","year":"2010","journal-title":"BMC Bioinformatics"},{"key":"2023020202215436200_btv203-B5","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1146\/annurev-biochem-060408-091030","article-title":"Origins of specificity in protein\u2013DNA recognition","volume":"79","author":"Rohs","year":"2010","journal-title":"Annu. 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Sci."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/31\/16\/2751\/49035428\/bioinformatics_31_16_2751.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/31\/16\/2751\/49035428\/bioinformatics_31_16_2751.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T03:45:57Z","timestamp":1675309557000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/31\/16\/2751\/321266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,16]]},"references-count":8,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015,8,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btv203","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2015,8,15]]},"published":{"date-parts":[[2015,4,16]]}}}