{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:21:03Z","timestamp":1781886063738,"version":"3.54.5"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"20","license":[{"start":{"date-parts":[[2016,10,2]],"date-time":"2016-10-02T00:00:00Z","timestamp":1475366400000},"content-version":"vor","delay-in-days":480,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Biological sequence diagrams are fundamental for visualizing various functional elements in protein or nucleotide sequences that enable a summarization and presentation of existing information as well as means of intuitive new discoveries. Here, we present a software package called illustrator of biological sequences (IBS) that can be used for representing the organization of either protein or nucleotide sequences in a convenient, efficient and precise manner. Multiple options are provided in IBS, and biological sequences can be manipulated, recolored or rescaled in a user-defined mode. Also, the final representational artwork can be directly exported into a publication-quality figure.<\/jats:p>\n               <jats:p>Availability and implementation: The standalone package of IBS was implemented in JAVA, while the online service was implemented in HTML5 and JavaScript. Both the standalone package and online service are freely available at http:\/\/ibs.biocuckoo.org.<\/jats:p>\n               <jats:p>Contact: \u00a0renjian.sysu@gmail.com or xueyu@hust.edu.cn<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv362","type":"journal-article","created":{"date-parts":[[2015,6,12]],"date-time":"2015-06-12T02:49:45Z","timestamp":1434077385000},"page":"3359-3361","source":"Crossref","is-referenced-by-count":886,"title":["IBS: an illustrator for the presentation and visualization of biological sequences"],"prefix":"10.1093","volume":"31","author":[{"given":"Wenzhong","family":"Liu","sequence":"first","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"},{"name":"2 Collaborative Innovation Center of High Performance Computing, National University of Defense Technology, Changsha 410073, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubin","family":"Xie","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyong","family":"Ma","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Luo","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Nie","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixiang","family":"Zuo","sequence":"additional","affiliation":[{"name":"3 Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"Lahrmann","sequence":"additional","affiliation":[{"name":"4 Fraunhofer Institute for Toxicology and Experimental Medicine, Project Group Personalized Tumor Therapy, 93053 Regensburg, Germany and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhao","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyuan","family":"Zheng","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhao","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xue","sequence":"additional","affiliation":[{"name":"5 Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ren","sequence":"additional","affiliation":[{"name":"1 State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510275, China,"},{"name":"2 Collaborative Innovation Center of High Performance Computing, National University of Defense Technology, Changsha 410073, China,"},{"name":"3 Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,6,10]]},"reference":[{"key":"2023020202331331600_btv362-B1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.4161\/nucl.21980","article-title":"The RanBP2\/RanGAP1*SUMO1\/Ubc9 complex: a multisubunit E3 ligase at the intersection of sumoylation and the RanGTPase cycle","volume":"3","author":"Flotho","year":"2012","journal-title":"Nucleus"},{"key":"2023020202331331600_btv362-B2","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1017\/S1462399411001992","article-title":"Bromodomains as therapeutic targets","volume":"13","author":"Muller","year":"2011","journal-title":"Expert Rev. Mol. 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