{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:01:38Z","timestamp":1767963698573,"version":"3.49.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Lysine succinylation orchestrates a variety of biological processes. Annotation of succinylation in proteomes is the first-crucial step to decipher physiological roles of succinylation implicated in the pathological processes. In this work, we developed a novel succinylation site online prediction tool, called SuccFind, which is constructed to predict the lysine succinylation sites based on two major categories of characteristics: sequence-derived features and evolutionary-derived information of sequence and via an enhanced feature strategy for further optimizations. The assessment results obtained from cross-validation suggest that SuccFind can provide more instructive guidance for further experimental investigation of protein succinylation.<\/jats:p>\n               <jats:p>Availability and implementation: A user-friendly server is freely available on the web at: http:\/\/bioinfo.ncu.edu.cn\/SuccFind.aspx<\/jats:p>\n               <jats:p>Contact: \u00a0jdqiu@ncu.edu.cn<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv439","type":"journal-article","created":{"date-parts":[[2015,8,11]],"date-time":"2015-08-11T01:50:30Z","timestamp":1439257830000},"page":"3748-3750","source":"Crossref","is-referenced-by-count":59,"title":["SuccFind: a novel succinylation sites online prediction tool via enhanced characteristic strategy"],"prefix":"10.1093","volume":"31","author":[{"given":"Hao-Dong","family":"Xu","sequence":"first","affiliation":[{"name":"1 Department of Chemistry,"}]},{"given":"Shao-Ping","family":"Shi","sequence":"additional","affiliation":[{"name":"2 Department of Mathematics, Nanchang University, Nanchang 330031, China and"}]},{"given":"Ping-Ping","family":"Wen","sequence":"additional","affiliation":[{"name":"1 Department of Chemistry,"}]},{"given":"Jian-Ding","family":"Qiu","sequence":"additional","affiliation":[{"name":"1 Department of Chemistry,"},{"name":"3 Department of Chemical Engineering, Pingxiang University, Pingxiang 337055, China"}]}],"member":"286","published-online":{"date-parts":[[2015,8,10]]},"reference":[{"key":"2023020202401722000_btv439-B1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-1-59745-535-0_4","article-title":"Uniprotkb\/swiss-prot","volume-title":"Plant Bioinformatics","author":"Boutet","year":"2007"},{"key":"2023020202401722000_btv439-B2","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.1207861","article-title":"Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase","volume":"334","author":"Du","year":"2011","journal-title":"Science"},{"key":"2023020202401722000_btv439-B3","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1093\/nar\/28.1.374","article-title":"AAindex: amino acid index database","volume":"28","author":"Kawashima","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"2023020202401722000_btv439-B4","doi-asserted-by":"crossref","first-page":"6087","DOI":"10.1021\/pr500992r","article-title":"Systematic Identification of the Lysine succinylation in the Protozoan Parasite Toxoplasma gondii","volume":"13","author":"Li","year":"2014","journal-title":"J. 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