{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T15:34:25Z","timestamp":1769268865218,"version":"3.49.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: Isotope tracer experiments are an invaluable technique to analyze and study the metabolism of biological systems. However, isotope labeling experiments are often affected by naturally abundant isotopes especially in cases where mass spectrometric methods make use of derivatization. The correction of these additive interferences\u2014in particular for complex isotopic systems\u2014is numerically challenging and still an emerging field of research. When positional information is generated via collision-induced dissociation, even more complex calculations for isotopic interference correction are necessary. So far, no freely available tools can handle tandem mass spectrometry data. We present isotope correction toolbox, a program that corrects tandem mass isotopomer data from tandem mass spectrometry experiments. Isotope correction toolbox is written in the multi-platform programming language Perl and, therefore, can be used on all commonly available computer platforms.<\/jats:p>\n               <jats:p>Availability and implementation: Source code and documentation can be freely obtained under the Artistic License or the GNU General Public License from: https:\/\/github.com\/jungreuc\/isotope_correction_toolbox\/<\/jats:p>\n               <jats:p>Contact: {christian.jungreuthmayer@boku.ac.at,juergen.zanghellini@boku.ac.at}<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv514","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T08:26:51Z","timestamp":1442564811000},"page":"154-156","source":"Crossref","is-referenced-by-count":38,"title":["<i>ICT<\/i>: isotope correction toolbox"],"prefix":"10.1093","volume":"32","author":[{"given":"Christian","family":"Jungreuthmayer","sequence":"first","affiliation":[{"name":"1 Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria,"},{"name":"2 Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria and"}]},{"given":"Stefan","family":"Neubauer","sequence":"additional","affiliation":[{"name":"1 Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria,"},{"name":"3 Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria"}]},{"given":"Teresa","family":"Mairinger","sequence":"additional","affiliation":[{"name":"1 Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria,"},{"name":"3 Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria"}]},{"given":"J\u00fcrgen","family":"Zanghellini","sequence":"additional","affiliation":[{"name":"1 Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria,"},{"name":"2 Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria and"}]},{"given":"Stephan","family":"Hann","sequence":"additional","affiliation":[{"name":"1 Austrian Centre of Industrial Biotechnology (ACIB), Vienna, Austria,"},{"name":"3 Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria"}]}],"member":"286","published-online":{"date-parts":[[2015,9,17]]},"reference":[{"key":"2023020110212092400_btv514-B1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.copbio.2012.10.011","article-title":"Tandem mass spectrometry for measuring stable-isotope labeling","volume":"24","author":"Antoniewicz","year":"2013","journal-title":"Curr. 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Bioeng."}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/32\/1\/154\/49016329\/bioinformatics_32_1_154.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/32\/1\/154\/49016329\/bioinformatics_32_1_154.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T21:23:55Z","timestamp":1675286635000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/32\/1\/154\/1742487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,17]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btv514","relation":{},"ISSN":["1367-4811","1367-4803"],"issn-type":[{"value":"1367-4811","type":"electronic"},{"value":"1367-4803","type":"print"}],"subject":[],"published-other":{"date-parts":[[2016,1,1]]},"published":{"date-parts":[[2015,9,17]]}}}