{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:49:13Z","timestamp":1783547353162,"version":"3.55.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2016,10,12]],"date-time":"2016-10-12T00:00:00Z","timestamp":1476230400000},"content-version":"vor","delay-in-days":391,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: The Plant Small RNAMaker Site (P-SAMS) is a web tool for the simple and automated design of artificial miRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) for efficient and specific targeted gene silencing in plants. P-SAMS includes two applications, P-SAMS amiRNA Designer and P-SAMS syn-tasiRNA Designer. The navigation through both applications is wizard-assisted, and the job runtime is relatively short. Both applications output the sequence of designed small RNA(s), and the sequence of the two oligonucleotides required for cloning into \u2018B\/c\u2019 compatible vectors.<\/jats:p>\n               <jats:p>Availability and implementation: The P-SAMS website is available at http:\/\/p-sams.carringtonlab.org.<\/jats:p>\n               <jats:p>Contact: \u00a0acarbonell@ibmcp.upv.es or nfahlgren@danforthcenter.org<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv534","type":"journal-article","created":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T08:26:51Z","timestamp":1442564811000},"page":"157-158","source":"Crossref","is-referenced-by-count":83,"title":["P-SAMS: a web site for plant artificial microRNA and synthetic <i>trans<\/i>-acting small interfering RNA design"],"prefix":"10.1093","volume":"32","author":[{"given":"Noah","family":"Fahlgren","sequence":"first","affiliation":[{"name":"Donald Danforth Plant Science Center, St. Louis, MO 63132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven T.","family":"Hill","sequence":"additional","affiliation":[{"name":"Donald Danforth Plant Science Center, St. Louis, MO 63132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Carrington","sequence":"additional","affiliation":[{"name":"Donald Danforth Plant Science Center, St. Louis, MO 63132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Carbonell","sequence":"additional","affiliation":[{"name":"Donald Danforth Plant Science Center, St. Louis, MO 63132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,9,17]]},"reference":[{"key":"2023020110214216600_btv534-B1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/978-1-4939-2453-0_3","article-title":"Bioinformatics tools for achieving better gene silencing in plants","volume":"1287","author":"Ahmed","year":"2015","journal-title":"Methods Mol. 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