{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:32:18Z","timestamp":1761676338972},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Motivation: MIEC-SVM is a structure-based method for predicting protein recognition specificity. Here, we present an automated MIEC-SVM pipeline providing an integrated and user-friendly workflow for construction and application of the MIEC-SVM models. This pipeline can handle standard amino acids and those with post-translational modifications (PTMs) or small molecules. Moreover, multi-threading and support to Sun Grid Engine (SGE) are implemented to significantly boost the computational efficiency.<\/jats:p>\n               <jats:p>Availability and implementation: The program is available at http:\/\/wanglab.ucsd.edu\/MIEC-SVM.<\/jats:p>\n               <jats:p>Contact: wei-wang@ucsd.edu<\/jats:p>\n               <jats:p>Supplementary information \u00a0: \u00a0Supplementary data available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btv666","type":"journal-article","created":{"date-parts":[[2015,11,15]],"date-time":"2015-11-15T01:38:21Z","timestamp":1447551501000},"page":"940-942","source":"Crossref","is-referenced-by-count":8,"title":["MIEC-SVM: automated pipeline for protein peptide\/ligand interaction prediction"],"prefix":"10.1093","volume":"32","author":[{"given":"Nan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard I.","family":"Ainsworth","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meixin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,11,14]]},"reference":[{"key":"2023020111565633400_btv666-B1","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/nbt.1489","article-title":"Predicting PDZ domain-peptide interactions from primary sequences","volume":"26","author":"Chen","year":"2008","journal-title":"Nat. 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