{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:29:04Z","timestamp":1778632144069,"version":"3.51.4"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary: OpenSegSPIM is an open access and user friendly 3D automatic quantitative analysis tool for Single Plane Illumination Microscopy data. The software is designed to extract, in a user-friendly way, quantitative relevant information from SPIM image stacks, such as the number of nuclei or cells. It provides quantitative measurement (volume, sphericity, distance, intensity) on Light Sheet Fluorescent Microscopy images.<\/jats:p>\n               <jats:p>Availability and implementation: freely available from http:\/\/www.opensegspim.weebly.com. Source code and binaries under BSD License.<\/jats:p>\n               <jats:p>Contact: \u00a0lgole@imcb.a-star.edu.sg or wmyu@imcb.a-star.edu.sg or sohail.ahmed@imb.a-star.edu.sg<\/jats:p>\n               <jats:p>Supplementary information: Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btw093","type":"journal-article","created":{"date-parts":[[2016,2,24]],"date-time":"2016-02-24T02:56:21Z","timestamp":1456282581000},"page":"2075-2077","source":"Crossref","is-referenced-by-count":15,"title":["OpenSegSPIM: a user-friendly segmentation tool for SPIM data"],"prefix":"10.1093","volume":"32","author":[{"given":"Laurent","family":"Gole","sequence":"first","affiliation":[{"name":"1 Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kok Haur","family":"Ong","sequence":"additional","affiliation":[{"name":"2 Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Boudier","sequence":"additional","affiliation":[{"name":"3 IPAL UMI 2955 (CNRS, UPMC, UJF, IMT, I2R, NUS), BioInformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 13867, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weimiao","family":"Yu","sequence":"additional","affiliation":[{"name":"2 Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohail","family":"Ahmed","sequence":"additional","affiliation":[{"name":"1 Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,2,22]]},"reference":[{"key":"2023020112332762600_btw093-B1","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1038\/nmeth.3632","article-title":"Whole-animal functional and developmental imaging with isotropic spatial resolution","volume":"12","author":"Chhetri","year":"2015","journal-title":"Nat. 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