{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T16:09:41Z","timestamp":1769875781517,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Summary : We present ChAsE, a cross-platform desktop application developed for interactive visualization, exploration and clustering of epigenomic data such as ChIP-seq experiments. ChAsE is designed and developed in close collaboration with several groups of biologists and bioinformaticians with a focus on usability and interactivity. Data can be analyzed through k-means clustering, specifying presence or absence of signal in epigenetic data and performing set operations between clusters. Results can be explored in an interactive heat map and profile plot interface and exported for downstream analysis or as high quality figures suitable for publications.<\/jats:p>\n               <jats:p>Availability and Implementation: Software, source code (MIT License), data and video tutorials available at http:\/\/chase.cs.univie.ac.at .<\/jats:p>\n               <jats:p>Contact : mkarimi@brc.ubc.ca or torsten.moeller@univie.ac.at<\/jats:p>\n               <jats:p>Supplementary information: \u00a0Supplementary data are available at Bioinformatics online.<\/jats:p>","DOI":"10.1093\/bioinformatics\/btw382","type":"journal-article","created":{"date-parts":[[2016,7,5]],"date-time":"2016-07-05T01:59:34Z","timestamp":1467683974000},"page":"3324-3326","source":"Crossref","is-referenced-by-count":40,"title":["ChAsE: chromatin analysis and exploration tool"],"prefix":"10.1093","volume":"32","author":[{"given":"Hamid","family":"Younesy","sequence":"first","affiliation":[{"name":"1 Graphics Usability and Visualization Lab, Simon Fraser University, Burnaby, Canada"},{"name":"2 Canada\u2019s Michael Smith Genome Sciences Centre, Vancouver, Canada"},{"name":"3 Biomedical Research Centre, University of British Columbia, Vancouver, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cydney B.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"2 Canada\u2019s Michael Smith Genome Sciences Centre, Vancouver, Canada"},{"name":"4 Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada"},{"name":"5 Department of Molecular Oncology, BC Cancer Agency, Vancouver, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew C.","family":"Lorincz","sequence":"additional","affiliation":[{"name":"6 Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.M.","family":"Jones","sequence":"additional","affiliation":[{"name":"2 Canada\u2019s Michael Smith Genome Sciences Centre, Vancouver, Canada"},{"name":"6 Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, Canada"},{"name":"7 Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad M.","family":"Karimi","sequence":"additional","affiliation":[{"name":"3 Biomedical Research Centre, University of British Columbia, Vancouver, Canada"},{"name":"6 Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torsten","family":"M\u00f6ller","sequence":"additional","affiliation":[{"name":"1 Graphics Usability and Visualization Lab, Simon Fraser University, Burnaby, Canada"},{"name":"8 Visualization and Data Analysis Lab, Faculty of Computer Science, University of Vienna, Wien, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,7,4]]},"reference":[{"key":"2023020113513463000_btw382-B1","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1038\/nmeth.3038","article-title":"Epiviz: interactive visual analytics for functional genomics data","volume":"11","author":"Chelaru","year":"2014","journal-title":"Nat. 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