{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T16:53:40Z","timestamp":1695228820226},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T00:00:00Z","timestamp":1480032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"Department of Biotechnology, Govt. of India","award":["BT\/PR3260\/BRB\/10\/967\/2011"],"award-info":[{"award-number":["BT\/PR3260\/BRB\/10\/967\/2011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Motivation<\/jats:title>\n                  <jats:p>The majority of data generated routinely from various experiments are essentially multivariate, often categorized with multiple experimental metadata. Analyzing such results with interactive visualizations often yields interesting and intuitive results which otherwise remains undisclosed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In this paper, we present Web-Igloo\u2014a GUI based interactive \u2018feature decomposition independent\u2019 multivariate data visualization platform. Web-Igloo is likely to be a valuable contribution in the field of visual data mining, especially for researchers working with but not limited to multi-omics data. To demonstrate its utility, we have used a metagenomic dataset pertaining to the effect of multiple doses of antibiotic treatment on the human gut microbiome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and Implementation<\/jats:title>\n                  <jats:p>http:\/\/metagenomics.atc.tcs.com\/webigloo and http:\/\/121.241.184.233\/webigloo [Freely available for academic use].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btw669","type":"journal-article","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T11:06:59Z","timestamp":1476788819000},"page":"615-617","source":"Crossref","is-referenced-by-count":3,"title":["Web-igloo: a web based platform for multivariate data visualization"],"prefix":"10.1093","volume":"33","author":[{"given":"Bhusan K","family":"Kuntal","sequence":"first","affiliation":[{"name":"Bio-Sciences R&D Division, TCS Research, Tata Research Development & Design Centre, Pune, Maharashtra , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmila S","family":"Mande","sequence":"additional","affiliation":[{"name":"Bio-Sciences R&D Division, TCS Research, Tata Research Development & Design Centre, Pune, Maharashtra , India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,11,25]]},"reference":[{"key":"2023020204430688400_btw669-B1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/wics.101","article-title":"Principal component analysis","volume":"2","author":"Abdi","year":"2010","journal-title":"WIREs Comp. Stat"},{"key":"2023020204430688400_btw669-B2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2307\/2984159","article-title":"The validity of comparative experiments","volume":"111","author":"Anscombe","year":"1948","journal-title":"J. R. Stat. Soc. Ser. A (General)"},{"key":"2023020204430688400_btw669-B3","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/nature09944","article-title":"Enterotypes of the human gut microbiome","volume":"473","author":"Arumugam","year":"2011","journal-title":"Nature"},{"key":"2023020204430688400_btw669-B4","doi-asserted-by":"crossref","first-page":"18563.","DOI":"10.1038\/srep18563","article-title":"Gut bacterial diversity of the tribes of India and comparison with the worldwide data","volume":"5","author":"Dehingia","year":"2015","journal-title":"Sci. Rep"},{"key":"2023020204430688400_btw669-B5","doi-asserted-by":"crossref","first-page":"4554","DOI":"10.1073\/pnas.1000087107","article-title":"Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation","volume":"108 Suppl 1","author":"Dethlefsen","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"2023020204430688400_btw669-B6","doi-asserted-by":"crossref","first-page":"bbw080.","DOI":"10.1093\/bib\/bbw080","article-title":"Exploring and visualizing multidimensional data in translational research platforms","author":"Dunn","year":"2016","journal-title":"Brief. Bioinf"},{"key":"2023020204430688400_btw669-B7","author":"Hoffman","year":"1997"},{"key":"2023020204430688400_btw669-B8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ygeno.2014.01.004","article-title":"Igloo-Plot: a tool for visualization of multidimensional datasets","volume":"103","author":"Kuntal","year":"2014","journal-title":"Genomics"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/4\/615\/49037924\/bioinformatics_33_4_615.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/4\/615\/49037924\/bioinformatics_33_4_615.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T04:48:17Z","timestamp":1675313297000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/33\/4\/615\/2624550"}},"subtitle":[],"editor":[{"given":"Jonathan","family":"Wren","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,11,25]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,2,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btw669","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,2,15]]},"published":{"date-parts":[[2016,11,25]]}}}