{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:10:40Z","timestamp":1768313440142,"version":"3.49.0"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T00:00:00Z","timestamp":1479772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"Centre of Research Excellence","award":["1079102"],"award-info":[{"award-number":["1079102"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>The Ark is an open-source web-based tool that allows researchers to manage health and medical research data for humans and animals without specialized database skills or programming expertise. The system provides data management for core research information including demographic, phenotype, biospecimen and pedigree data, in addition to supporting typical investigator requirements such as tracking participant consent and correspondence, whilst also being able to generate custom data exports and reports. The Ark is \u2018study generic\u2019 by design and highly configurable via its web interface, allowing researchers to tailor the system to the specific data management requirements of their study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and Implementation<\/jats:title>\n                  <jats:p>Source code for The Ark can be obtained freely from the website https:\/\/github.com\/The-Ark-Informatics\/ark\/. The source code can be modified and redistributed under the terms of the GNU GPL v3 license. Documentation and a pre-configured virtual appliance can be found at the website http:\/\/sphinx.org.au\/the-ark\/.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btw675","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T11:07:09Z","timestamp":1477652829000},"page":"624-626","source":"Crossref","is-referenced-by-count":7,"title":["The Ark: a customizable web-based data management tool for health and medical research"],"prefix":"10.1093","volume":"33","author":[{"given":"Adrian","family":"Bickerstaffe","sequence":"first","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, The University of Melbourne, Carlton, Australia"}]},{"given":"Thilina","family":"Ranaweera","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, The University of Melbourne, Carlton, Australia"}]},{"given":"Travis","family":"Endersby","sequence":"additional","affiliation":[{"name":"Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University, Bentley, Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, Perth, Australia"}]},{"given":"Christopher","family":"Ellis","sequence":"additional","affiliation":[{"name":"Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University, Bentley, Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, Perth, Australia"}]},{"given":"Sanjaya","family":"Maddumarachchi","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, The University of Melbourne, Carlton, Australia"}]},{"given":"George E","family":"Gooden","sequence":"additional","affiliation":[{"name":"Genetics and Epidemiology, Lions Eye Institute, Nedlands, Australia"}]},{"given":"Paul","family":"White","sequence":"additional","affiliation":[{"name":"Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University, Bentley, Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, Perth, Australia"}]},{"given":"Eric K","family":"Moses","sequence":"additional","affiliation":[{"name":"Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University, Bentley, Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, Perth, Australia"}]},{"given":"Alex W","family":"Hewitt","sequence":"additional","affiliation":[{"name":"Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia"}]},{"given":"John L","family":"Hopper","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, The University of Melbourne, Carlton, Australia"}]}],"member":"286","published-online":{"date-parts":[[2016,11,22]]},"reference":[{"key":"2023020204415319200_btw675-B1","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1111\/ceo.12020","article-title":"Establishment and evolution of the Australian Inherited Retinal Disease Register and DNA Bank","volume":"41","author":"DeRoach","year":"2013","journal-title":"Clin. Exp. Ophthalmol"},{"key":"2023020204415319200_btw675-B2","first-page":"72.","article-title":"Lifepool: a collaboration between women and researchers","volume":"9","author":"Devereaux","year":"2014","journal-title":"Biopreserv. Biobank"},{"key":"2023020204415319200_btw675-B3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research Electronic Data Capture (REDCap) \u2013 a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform"},{"key":"2023020204415319200_btw675-B4","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/bioinformatics\/btm242","article-title":"Madeline 2.0 PDE: a new program for local and web-based pedigree drawing","volume":"23","author":"Trager","year":"2007","journal-title":"Bioinformatics"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/4\/624\/49037470\/bioinformatics_33_4_624.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/4\/624\/49037470\/bioinformatics_33_4_624.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T04:46:06Z","timestamp":1675313166000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/33\/4\/624\/2617575"}},"subtitle":[],"editor":[{"given":"Janet","family":"Kelso","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2016,11,22]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,2,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btw675","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,2,15]]},"published":{"date-parts":[[2016,11,22]]}}}