{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:39:17Z","timestamp":1760985557626},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T00:00:00Z","timestamp":1486684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"ERC Advanced"},{"name":"University Concerted Research Action"},{"name":"VLAIO SBO"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>We describe sfinx, an R package providing access to the straightforward filtering index (SFINX) for the separation of true positive from false positive protein interactions in affinity purification \u2013 mass spectrometry datasets. This package maintains the reliability and user-friendliness of the SFINX web site interface but is faster, unlimited in input size, and can be run locally within R.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and Implementation<\/jats:title>\n                  <jats:p>The sfinx R package is available for download at the comprehensive R archive network (CRAN) https:\/\/cran.r-project.org\/web\/packages\/sfinx\/ under the Apache License 2.0.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx076","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T10:41:30Z","timestamp":1486723290000},"page":"1902-1904","source":"Crossref","is-referenced-by-count":4,"title":["sfinx: an R package for the elimination of false positives from affinity purification\u2013mass spectrometry datasets"],"prefix":"10.1093","volume":"33","author":[{"given":"Kevin","family":"Titeca","sequence":"first","affiliation":[{"name":"VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium"},{"name":"Department of Biochemistry, Ghent University, Ghent, Belgium"}]},{"given":"Pieter","family":"Meysman","sequence":"additional","affiliation":[{"name":"Advanced Database Research and Modelling (ADReM), Department of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium"},{"name":"Biomedical Informatics Research Center Antwerp (biomina), University of Antwerp\/Antwerp University Hospital, Edegem, Belgium"}]},{"given":"Kris","family":"Laukens","sequence":"additional","affiliation":[{"name":"Advanced Database Research and Modelling (ADReM), Department of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium"},{"name":"Biomedical Informatics Research Center Antwerp (biomina), University of Antwerp\/Antwerp University Hospital, Edegem, Belgium"}]},{"given":"Lennart","family":"Martens","sequence":"additional","affiliation":[{"name":"VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium"},{"name":"Department of Biochemistry, Ghent University, Ghent, Belgium"},{"name":"Bioinformatics Institute Ghent, Ghent University, Zwijnaarde, Belgium"}]},{"given":"Jan","family":"Tavernier","sequence":"additional","affiliation":[{"name":"VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium"},{"name":"Department of Biochemistry, Ghent University, Ghent, Belgium"}]},{"given":"Sven","family":"Eyckerman","sequence":"additional","affiliation":[{"name":"VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium"},{"name":"Department of Biochemistry, Ghent University, Ghent, Belgium"}]}],"member":"286","published-online":{"date-parts":[[2017,2,10]]},"reference":[{"key":"2023020205404987700_btx076-B1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nmeth.1541","article-title":"SAINT: probabilistic scoring of affinity purification-mass spectrometry data","volume":"8","author":"Choi","year":"2011","journal-title":"Nat. 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