{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T21:04:23Z","timestamp":1715979863427},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"13","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Motivation<\/jats:title>\n                  <jats:p>While large amounts of epigenomic data are publicly available, their retrieval in a form suitable for downstream analysis is a bottleneck in current research. The DeepBlue Epigenomic Data Server provides a powerful interface and API for filtering, transforming, aggregating and downloading data from several epigenomic consortia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>To make public epigenomic data conveniently available for analysis in R, we developed an R\/Bioconductor package that connects to the DeepBlue Epigenomic Data Server, enabling users to quickly gather and transform epigenomic data from selected experiments for analysis in the Bioconductor ecosystem.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and Implementation<\/jats:title>\n                  <jats:p>http:\/\/deepblue.mpi-inf.mpg.de\/R.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Requirements<\/jats:title>\n                  <jats:p>R 3.3, Bioconductor 3.4.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx099","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T20:13:52Z","timestamp":1487708032000},"page":"2063-2064","source":"Crossref","is-referenced-by-count":6,"title":["DeepBlueR: large-scale epigenomic analysis in R"],"prefix":"10.1093","volume":"33","author":[{"given":"Felipe","family":"Albrecht","sequence":"first","affiliation":[{"name":"Max Planck Institute for Informatics, Saarland Informatics Campus, Saarbr\u00fccken, Germany"},{"name":"Graduate School of Computer Science, Saarland Informatics Campus, Saarbr\u00fccken, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"List","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Informatics, Saarland Informatics Campus, Saarbr\u00fccken, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Bock","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Informatics, Saarland Informatics Campus, Saarbr\u00fccken, Germany"},{"name":"CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Medical University of Vienna, Vienna, Austria"},{"name":"Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Lengauer","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Informatics, Saarland Informatics Campus, Saarbr\u00fccken, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,2,22]]},"reference":[{"key":"2023020206013047500_btx099-B1","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/nbt.2153","article-title":"BLUEPRINT to decode the epigenetic signature written in blood","volume":"30","author":"Adams","year":"2012","journal-title":"Nat. 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