{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T16:42:27Z","timestamp":1776012147346,"version":"3.50.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"14","license":[{"start":{"date-parts":[[2017,3,11]],"date-time":"2017-03-11T00:00:00Z","timestamp":1489190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,15]]},"abstract":"Abstract<\/jats:title>\n \n Motivation<\/jats:title>\n Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks.<\/jats:p>\n <\/jats:sec>\n \n Availability and Implementation<\/jats:title>\n Dynamix is hosted at http:\/\/furlonglab.embl.de\/Dynamix.<\/jats:p>\n <\/jats:sec>\n \n Supplementary information<\/jats:title>\n Supplementary data are available at Bioinformatics online.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx141","type":"journal-article","created":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T12:31:33Z","timestamp":1489149093000},"page":"2194-2196","source":"Crossref","is-referenced-by-count":4,"title":["Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets"],"prefix":"10.1093","volume":"33","author":[{"given":"Matthias","family":"Monfort","sequence":"first","affiliation":[{"name":"European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany"}]},{"given":"Eileen E M","family":"Furlong","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany"}]},{"given":"Charles","family":"Girardot","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany"}]}],"member":"286","published-online":{"date-parts":[[2017,3,11]]},"reference":[{"key":"2023051506471482200_btx141-B1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature11247","article-title":"An integrated encyclopedia of DNA elements in the human genome","volume":"489","author":"Consortium,T.E.P.","year":"2012","journal-title":"Nature"},{"key":"2023051506471482200_btx141-B2","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot093062","article-title":"Visualizing genomic annotations with the UCSC genome browser","volume":"2016","author":"Hung","year":"2016","journal-title":"Cold Spring Harb. Protoc"},{"key":"2023051506471482200_btx141-B3","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1093\/bib\/bbt001","article-title":"Using GBrowse 2.0 to visualize and share next-generation sequence data","volume":"14","author":"Stein","year":"2013","journal-title":"Brief. Bioinf"},{"key":"2023051506471482200_btx141-B4","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/bib\/bbs017","article-title":"Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration","volume":"14","author":"Thorvaldsdottir","year":"2013","journal-title":"Brief. Bioinf"},{"key":"2023051506471482200_btx141-B5","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/bib\/bbr078","article-title":"Visualizing next-generation sequencing data with JBrowse","volume":"14","author":"Westesson","year":"2013","journal-title":"Brief. Bioinf"},{"key":"2023051506471482200_btx141-B6","doi-asserted-by":"crossref","first-page":"D710","DOI":"10.1093\/nar\/gkv1157","article-title":"Ensembl 2016","volume":"44","author":"Yates","year":"2016","journal-title":"Nucleic Acids Res"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/14\/2194\/50314747\/bioinformatics_33_14_2194.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/14\/2194\/50314747\/bioinformatics_33_14_2194.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T06:47:29Z","timestamp":1684133249000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/33\/14\/2194\/3066292"}},"subtitle":[],"editor":[{"given":"John","family":"Hancock","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2017,3,11]]},"references-count":6,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2017,7,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btx141","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,7,15]]},"published":{"date-parts":[[2017,3,11]]}}}