{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T03:28:41Z","timestamp":1776482921461,"version":"3.51.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T00:00:00Z","timestamp":1498089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R00HG007583"],"award-info":[{"award-number":["R00HG007583"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U54HG007963"],"award-info":[{"award-number":["U54HG007963"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01CA198935"],"award-info":[{"award-number":["U01CA198935"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Motivation<\/jats:title>\n                    <jats:p>Venn and Euler diagrams are a popular yet inadequate solution for quantitative visualization of set intersections. A scalable alternative to Venn and Euler diagrams for visualizing intersecting sets and their properties is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We developed UpSetR, an open source R package that employs a scalable matrix-based visualization to show intersections of sets, their size, and other properties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>UpSetR is available at https:\/\/github.com\/hms-dbmi\/UpSetR\/ and released under the MIT License. A Shiny app is available at https:\/\/gehlenborglab.shinyapps.io\/upsetr\/.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx364","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T04:23:32Z","timestamp":1496723012000},"page":"2938-2940","source":"Crossref","is-referenced-by-count":3223,"title":["UpSetR: an R package for the visualization of intersecting sets and their properties"],"prefix":"10.1093","volume":"33","author":[{"given":"Jake R","family":"Conway","sequence":"first","affiliation":[{"name":"Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA"}]},{"given":"Alexander","family":"Lex","sequence":"additional","affiliation":[{"name":"SCI Institute, School of Computing, University of Utah, Salt Lake City, UT, USA"}]},{"given":"Nils","family":"Gehlenborg","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA"}]}],"member":"286","published-online":{"date-parts":[[2017,6,22]]},"reference":[{"key":"2023020206401084300_btx364-B1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/cgf.12722","article-title":"The State-of-the-Art of Set Visualization","volume":"35","author":"Alsallakh","year":"2016","journal-title":"Computer Graphics Forum"},{"key":"2023020206401084300_btx364-B2","doi-asserted-by":"crossref","first-page":"35.","DOI":"10.1186\/1471-2105-12-35","article-title":"VennDiagram: a package for the generation of highly-customizable Venn & Euler diagrams in R","volume":"12","author":"Chen","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"2023020206401084300_btx364-B3","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/01621459.1984.10478080","article-title":"Graphical perception: Theory, experimentation, and application to the development of graphical methods","volume":"79","author":"Cleveland","year":"1984","journal-title":"J. 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