{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T21:50:31Z","timestamp":1687643431728},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"19","license":[{"start":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T00:00:00Z","timestamp":1497484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>We introduce matter, an R package for direct interactions with larger-than-memory datasets, stored in an arbitrary number of files of any size. matter is primarily designed for datasets in new and rapidly evolving file formats, which may lack extensive software support. matter enables a wide variety of data exploration and manipulation steps and is extensible to many bioinformatics applications. It supports reproducible research by minimizing the need of converting and storing data in multiple formats. We illustrate the performance of matter in conjunction with the Bioconductor package Cardinal for analysis of high-resolution, high-throughput mass spectrometry imaging experiments.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>The package, vignettes and examples of applications in several areas of bioinformatics are available open-source at www.bioconductor.org under the Artistic-2.0 license.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx392","type":"journal-article","created":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T03:10:57Z","timestamp":1497409857000},"page":"3142-3144","source":"Crossref","is-referenced-by-count":3,"title":["matter: an R package for rapid prototyping with larger-than-memory datasets on disk"],"prefix":"10.1093","volume":"33","author":[{"given":"Kylie A","family":"Bemis","sequence":"first","affiliation":[{"name":"College of Computer and Information Science, Northeastern University, Boston, MA, USA"}]},{"given":"Olga","family":"Vitek","sequence":"additional","affiliation":[{"name":"College of Computer and Information Science, Northeastern University, Boston, MA, USA"},{"name":"Department of Chemistry and Chemical Biology, College of Science, Northeastern University, Boston, MA, USA"}]}],"member":"286","published-online":{"date-parts":[[2017,6,15]]},"reference":[{"key":"2023020206464281900_btx392-B1","author":"Adler","year":"2014"},{"key":"2023020206464281900_btx392-B2","author":"Baglama","year":"2015"},{"key":"2023020206464281900_btx392-B3","doi-asserted-by":"crossref","first-page":"2418.","DOI":"10.1093\/bioinformatics\/btv146","article-title":"Cardinal: an R package for statistical analysis of mass spectrometry-based imaging experiments","volume":"31","author":"Bemis","year":"2015","journal-title":"Bioinformatics"},{"key":"2023020206464281900_btx392-B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v055.i14","article-title":"Scalable strategies for computing with massive data","volume":"55","author":"Kane","year":"2013","journal-title":"J. Stat. Softw"},{"key":"2023020206464281900_btx392-B5","author":"Lumley","year":"2013"},{"key":"2023020206464281900_btx392-B6","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1186\/s13742-015-0059-4","article-title":"Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry","volume":"4","author":"Oetjen","year":"2015","journal-title":"GigaScience"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/19\/3142\/49041259\/bioinformatics_33_19_3142.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/33\/19\/3142\/49041259\/bioinformatics_33_19_3142.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T06:46:54Z","timestamp":1675320414000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/33\/19\/3142\/3868724"}},"subtitle":[],"editor":[{"given":"Jonathan","family":"Wren","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2017,6,15]]},"references-count":6,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2017,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/btx392","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,10,1]]},"published":{"date-parts":[[2017,6,15]]}}}