{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:15:29Z","timestamp":1769073329850,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"23","license":[{"start":{"date-parts":[[2017,8,17]],"date-time":"2017-08-17T00:00:00Z","timestamp":1502928000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["RO1CA180006"],"award-info":[{"award-number":["RO1CA180006"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA178383"],"award-info":[{"award-number":["R01CA178383"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U24CA2110006"],"award-info":[{"award-number":["U24CA2110006"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>MIRMMR predicts microsatellite instability status in cancer samples using methylation and mutation information, in contrast to existing methods that rely on observed microsatellites. Additionally, MIRMMR highlights those genetic alterations contributing to microsatellite instability.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>Source code is freely available at https:\/\/github.com\/ding-lab\/MIRMMR under the MIT license, implemented in R and supported on Unix\/OS X operating systems.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx507","type":"journal-article","created":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T19:13:47Z","timestamp":1502306027000},"page":"3799-3801","source":"Crossref","is-referenced-by-count":19,"title":["MIRMMR: binary classification of microsatellite instability using methylation and mutations"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9526-8194","authenticated-orcid":false,"given":"Steven M","family":"Foltz","sequence":"first","affiliation":[{"name":"Oncology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA"}]},{"given":"Wen-Wei","family":"Liang","sequence":"additional","affiliation":[{"name":"Oncology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA"}]},{"given":"Mingchao","family":"Xie","sequence":"additional","affiliation":[{"name":"Oncology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA"}]},{"given":"Li","family":"Ding","sequence":"additional","affiliation":[{"name":"Oncology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA"},{"name":"Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA"}]}],"member":"286","published-online":{"date-parts":[[2017,8,17]]},"reference":[{"key":"2023020207010170600_btx507-B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v033.i01","article-title":"Regularization paths for generalized linear models via coordinate descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J. 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