{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T16:06:11Z","timestamp":1775837171178,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T00:00:00Z","timestamp":1512172800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004199","name":"Okinawa Institute of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,15]]},"abstract":"Abstract<\/jats:title>\n \n Motivation<\/jats:title>\n Functional and taxonomic analyses are critical steps in understanding interspecific interactions within microbial communities. Currently, such analyses are run separately, which complicates interpretation of results. Here we present the ASAR interactive tool for simultaneous analysis of metagenomic data in three dimensions: taxonomy, function, metagenome.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n An interactive data analysis tool for selection, aggregation and visualization of metagenomic data is presented. Functional analysis with a SEED hierarchy and pathway diagram based on KEGG orthology based upon MG-RAST annotation results is available.<\/jats:p>\n <\/jats:sec>\n \n Availability and implementation<\/jats:title>\n Source code of the ASAR is accessible at GitHub (https:\/\/github.com\/Askarbek-orakov\/ASAR).<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx775","type":"journal-article","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T15:44:20Z","timestamp":1512143060000},"page":"1404-1405","source":"Crossref","is-referenced-by-count":6,"title":["ASAR: visual analysis of metagenomes in R"],"prefix":"10.1093","volume":"34","author":[{"given":"Askarbek N","family":"Orakov","sequence":"first","affiliation":[{"name":"Biological Systems Unit, Okinawa Institute of Science and Technology, Onna-son, Japan"},{"name":"Department of Biology, School of Science and Technology, Nazarbayev University, Astana, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazgul K","family":"Sakenova","sequence":"additional","affiliation":[{"name":"Biological Systems Unit, Okinawa Institute of Science and Technology, Onna-son, Japan"},{"name":"Department of Biology, School of Science and Technology, Nazarbayev University, Astana, Kazakhstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anatoly","family":"Sorokin","sequence":"additional","affiliation":[{"name":"Mechanism of Cell Genome Functioning Laboratory, Institute of Cell Biophysics RAS, Pushchino, Russia"},{"name":"Laboratory of Ion and Molecular Physics, Moscow Institute of Physics and Technology, Dolgoprundy, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor I","family":"Goryanin","sequence":"additional","affiliation":[{"name":"Biological Systems Unit, Okinawa Institute of Science and Technology, Onna-son, Japan"},{"name":"School of Informatics, University of Edinburgh, Edinburgh, UK"},{"name":"Biodesign Centre, Tianjin Institute of Industrial Biotechnology, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,12,1]]},"reference":[{"key":"2023012713010931600_btx775-B1","author":"Chang","year":"2016"},{"key":"2023012713010931600_btx775-B2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/455481a","article-title":"Microbiology: metagenomics","volume":"455","author":"Hugenholtz","year":"2008","journal-title":"Nature"},{"key":"2023012713010931600_btx775-B3","doi-asserted-by":"crossref","first-page":"D457","DOI":"10.1093\/nar\/gkv1070","article-title":"KEGG as a reference resource for gene and protein annotation","volume":"44","author":"Kanehisa","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"2023012713010931600_btx775-B4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/978-1-4939-3369-3_13","article-title":"MG-RAST, a metagenomics service for analysis of microbial community structure and function","volume":"1399","author":"Keegan","year":"2016","journal-title":"Methods Mol. 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