{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T09:21:15Z","timestamp":1773480075054,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T00:00:00Z","timestamp":1513900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"ERC","doi-asserted-by":"publisher","award":["322621"],"award-info":[{"award-number":["322621"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Motivation<\/jats:title><jats:p>Next Generation Sequencing (NGS) technologies generate a large amount of high quality transcriptome datasets enabling the investigation of molecular processes on a genomic and metagenomic scale. These transcriptomics studies aim to quantify and compare the molecular phenotypes of the biological processes at hand. Despite the vast increase of available transcriptome datasets, little is known about the evolutionary conservation of those characterized transcriptomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The myTAI package implements exploratory analysis functions to infer transcriptome conservation patterns in any transcriptome dataset. Comprehensive documentation of myTAI functions and tutorial vignettes provide step-by-step instructions on how to use the package in an exploratory and computationally reproducible manner.<\/jats:p><\/jats:sec><jats:sec><jats:title>Availability and implementation<\/jats:title><jats:p>The open source myTAI package is available at https:\/\/github.com\/HajkD\/myTAI and https:\/\/cran.r-project.org\/web\/packages\/myTAI\/index.html.<\/jats:p><\/jats:sec><jats:sec><jats:title>Supplementary information<\/jats:title><jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p><\/jats:sec>","DOI":"10.1093\/bioinformatics\/btx835","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T04:56:25Z","timestamp":1513918585000},"page":"1589-1590","source":"Crossref","is-referenced-by-count":69,"title":["myTAI: evolutionary transcriptomics with R"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1567-306X","authenticated-orcid":false,"given":"Hajk-Georg","family":"Drost","sequence":"first","affiliation":[{"name":"Sainsbury Laboratory Cambridge, University of Cambridge, Cambridge, UK"},{"name":"Institute of Computer Science, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany"}]},{"given":"Alexander","family":"Gabel","sequence":"additional","affiliation":[{"name":"Institute of Computer Science, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany"}]},{"given":"Jialin","family":"Liu","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Lausanne, D\u00e9partement d\u2019Ecologie et d\u2019Evolution, Quartier Sorge, Lausanne, Switzerland"}]},{"given":"Marcel","family":"Quint","sequence":"additional","affiliation":[{"name":"Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany"}]},{"given":"Ivo","family":"Grosse","sequence":"additional","affiliation":[{"name":"Institute of Computer Science, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany"},{"name":"German Center for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Leipzig, Germany"}]}],"member":"286","published-online":{"date-parts":[[2017,12,22]]},"reference":[{"key":"2023012713030951300_btx835-B1","doi-asserted-by":"crossref","first-page":"191.","DOI":"10.12688\/f1000research.2-191.v1","article-title":"taxize: taxonomic search and retrieval in R","volume":"2","author":"Chamberlain","year":"2013","journal-title":"F1000Research"},{"key":"2023012713030951300_btx835-B2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v064.i04","article-title":"fitdistrplus: an R package for fitting distributions","volume":"64","author":"Delignette-Muller","year":"2015","journal-title":"J. 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