{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:03:43Z","timestamp":1771473823961,"version":"3.50.1"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T00:00:00Z","timestamp":1517875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"BBMRI-NL"},{"DOI":"10.13039\/501100003246","name":"NWO","doi-asserted-by":"publisher","award":["184.021.007"],"award-info":[{"award-number":["184.021.007"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"NWO","doi-asserted-by":"publisher","award":["184.033.111"],"award-info":[{"award-number":["184.033.111"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>OmicsPrint is a versatile method for the detection of data linkage errors in multiple omics studies encompassing genetic, transcriptome and\/or methylome data. OmicsPrint evaluates data linkage within and between omics data types using genotype calls from SNP arrays, DNA- or RNA-sequencing data and includes an algorithm to infer genotypes from Illumina DNA methylation array data. The method uses classification to verify assumed relationships and detect any data linkage errors, e.g. arising from sample mix-ups and mislabeling. Graphical and text output is provided to inspect and resolve putative data linkage errors. If sufficient genotype calls are available, first degree family relations also are revealed which can be used to check parent\u2013offspring relations or zygosity in twin studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>omicsPrint is available from BioConductor; http:\/\/bioconductor.org\/packages\/omicsPrint.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/bty062","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T12:08:49Z","timestamp":1517832529000},"page":"2142-2143","source":"Crossref","is-referenced-by-count":35,"title":["omicsPrint: detection of data linkage errors in multiple omics studies"],"prefix":"10.1093","volume":"34","author":[{"given":"Maarten","family":"van Iterson","sequence":"first","affiliation":[{"name":"Molecular Epidemiology, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, ZC Leiden, The Netherlands"}]},{"given":"Davy","family":"Cats","sequence":"additional","affiliation":[{"name":"Molecular Epidemiology, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, ZC Leiden, The Netherlands"}]},{"given":"Paul","family":"Hop","sequence":"additional","affiliation":[{"name":"Molecular Epidemiology, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, ZC Leiden, The Netherlands"}]},{"name":"BIOS Consortium","sequence":"additional","affiliation":[]},{"given":"Bastiaan T","family":"Heijmans","sequence":"additional","affiliation":[{"name":"Molecular Epidemiology, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, ZC Leiden, The Netherlands"}]}],"member":"286","published-online":{"date-parts":[[2018,2,6]]},"reference":[{"key":"2023012713394854400_bty062-B1","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/bioinformatics\/17.8.742","article-title":"GRR: graphical representation of relationship errors","volume":"17","author":"Abecasis","year":"2001","journal-title":"Bioinformatics"},{"key":"2023012713394854400_bty062-B2","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/nature08990","article-title":"Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis","volume":"464","author":"Baranzini","year":"2010","journal-title":"Nature"},{"key":"2023012713394854400_bty062-B3","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/526052a","article-title":"Human genomics: the end of the start for population sequencing","volume":"526","author":"Birney","year":"2015","journal-title":"Nature"},{"key":"2023012713394854400_bty062-B4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/ng.3721","article-title":"Disease variants alter transcription factor levels and methylation of their binding sites","volume":"49","author":"Bonder","year":"2017","journal-title":"Nat. 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