{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T05:47:31Z","timestamp":1780552051331,"version":"3.54.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"16","license":[{"start":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T00:00:00Z","timestamp":1546387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CCF-1563942"],"award-info":[{"award-number":["CCF-1563942"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CCF-1564132"],"award-info":[{"award-number":["CCF-1564132"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CCF-1319632"],"award-info":[{"award-number":["CCF-1319632"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DMS-1760448"],"award-info":[{"award-number":["DMS-1760448"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CCF-1708884"],"award-info":[{"award-number":["CCF-1708884"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009226","name":"National Security Agency","doi-asserted-by":"publisher","award":["#H98230-18-1-0016"],"award-info":[{"award-number":["#H98230-18-1-0016"]}],"id":[{"id":"10.13039\/100009226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006462","name":"City University of New York","doi-asserted-by":"publisher","award":["PSC-CUNY #69827-00 47"],"award-info":[{"award-number":["PSC-CUNY #69827-00 47"]}],"id":[{"id":"10.13039\/100006462","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006462","name":"City University of New York","doi-asserted-by":"publisher","award":["#60098-00 48"],"award-info":[{"award-number":["#60098-00 48"]}],"id":[{"id":"10.13039\/100006462","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Biological processes are often modeled by ordinary differential equations with unknown parameters. The unknown parameters are usually estimated from experimental data. In some cases, due to the structure of the model, this estimation problem does not have a unique solution even in the case of continuous noise-free data. It is therefore desirable to check the uniqueness a priori before carrying out actual experiments. We present a new software SIAN (Structural Identifiability ANalyser) that does this. Our software can tackle problems that could not be tackled by previously developed packages.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>SIAN is open-source software written in Maple and is available at https:\/\/github.com\/pogudingleb\/SIAN.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/bty1069","type":"journal-article","created":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T12:11:20Z","timestamp":1545999080000},"page":"2873-2874","source":"Crossref","is-referenced-by-count":112,"title":["SIAN: software for structural identifiability analysis of ODE models"],"prefix":"10.1093","volume":"35","author":[{"given":"Hoon","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Mathematics, North Carolina State University, Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey","family":"Ovchinnikov","sequence":"additional","affiliation":[{"name":"Department of Mathematics, CUNY Queens College and Ph.D. Programs in Mathematics and Computer Science, CUNY Graduate Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gleb","family":"Pogudin","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Courant Institute of Mathematical Sciences, New York University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee","family":"Yap","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Courant Institute of Mathematical Sciences, New York University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,1,2]]},"reference":[{"key":"2023062803480104600_bty1069-B1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cmpb.2007.07.002","article-title":"DAISY: a new software tool to test global identifiability of biological and physiological systems","volume":"88","author":"Bellu","year":"2007","journal-title":"Comput. 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