{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T03:54:45Z","timestamp":1770609285135,"version":"3.49.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2018,4,20]],"date-time":"2018-04-20T00:00:00Z","timestamp":1524182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Antimicrobial Research Collaborative"},{"DOI":"10.13039\/501100000761","name":"Imperial College London","doi-asserted-by":"publisher","award":["RSRO_54990"],"award-info":[{"award-number":["RSRO_54990"]}],"id":[{"id":"10.13039\/501100000761","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000270","name":"Natural Environment Research Council","doi-asserted-by":"publisher","award":["NE\/P001165\/1"],"award-info":[{"award-number":["NE\/P001165\/1"]}],"id":[{"id":"10.13039\/501100000270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>The increase of antifungal drug resistance is a major global human health concern and threatens agriculture and food security; in order to tackle these concerns, it is important to understand the mechanisms that cause antifungal resistance. The curated Mycology Antifungal Resistance Database (MARDy) is a web-service of antifungal drug resistance mechanisms, including amino acid substitutions, tandem repeat sequences and genome ploidy. MARDy is implemented on a Linux, Apache, MySQL and PHP web development platform and includes a local installation of BLASTn of the database of curated genes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>MARDy can be accessed at http:\/\/www.mardy.net and is free to use. The complete database can be retrieved, ordered by organism, gene and drug. Missing or new mycological antifungal resistance data can be relayed to the development team through a contribute entry form. Updates and news will be publicized via a dedicated Twitter feed: @MARDYfungi.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/bty321","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T11:12:57Z","timestamp":1524136377000},"page":"3233-3234","source":"Crossref","is-referenced-by-count":44,"title":["MARDy: Mycology Antifungal Resistance Database"],"prefix":"10.1093","volume":"34","author":[{"given":"Anthony","family":"Nash","sequence":"first","affiliation":[{"name":"Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK"},{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"}]},{"given":"Thomas","family":"Sewell","sequence":"additional","affiliation":[{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"}]},{"given":"Rhys A","family":"Farrer","sequence":"additional","affiliation":[{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"},{"name":"Genome Sequencing and Analysis Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA"}]},{"given":"Alireza","family":"Abdolrasouli","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, UK"},{"name":"Department of Medical Microbiology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK"}]},{"given":"Jennifer M G","family":"Shelton","sequence":"additional","affiliation":[{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"}]},{"given":"Matthew C","family":"Fisher","sequence":"additional","affiliation":[{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1338-7860","authenticated-orcid":false,"given":"Johanna","family":"Rhodes","sequence":"additional","affiliation":[{"name":"MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK"}]}],"member":"286","published-online":{"date-parts":[[2018,4,20]]},"reference":[{"key":"2023012704180959600_bty321-B1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nature10947","article-title":"Emerging fungal threats to animal, plant and ecosystem health","volume":"484","author":"Fisher","year":"2012","journal-title":"Nature"},{"key":"2023012704180959600_bty321-B2","doi-asserted-by":"crossref","first-page":"D699","DOI":"10.1093\/nar\/gkt1183","article-title":"MycoCosm portal: gearing up for 1000 fungal genomes","volume":"24","author":"Grigoriev","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"2023012704180959600_bty321-B3","doi-asserted-by":"crossref","first-page":"D566","DOI":"10.1093\/nar\/gkw1004","article-title":"CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database","volume":"45","author":"Jia","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"2023012704180959600_bty321-B4","doi-asserted-by":"crossref","first-page":"D443","DOI":"10.1093\/nar\/gkn656","article-title":"ARDB: antibiotic resistance genes database","volume":"37","author":"Liu","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"2023012704180959600_bty321-B5","doi-asserted-by":"crossref","first-page":"D675","DOI":"10.1093\/nar\/gkr918","article-title":"FungiDB: an integrated functional genomics database for fungi","volume":"40","author":"Stajich","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"2023012704180959600_bty321-B6","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/mmy\/myx015","article-title":"FunResDB-A web resource for genotypic susceptibility testing of Aspergillus fumigatus","volume":"56","author":"Weber","year":"2018","journal-title":"Med. 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B"}],"container-title":["Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/34\/18\/3233\/48919448\/bioinformatics_34_18_3233.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article-pdf\/34\/18\/3233\/48919448\/bioinformatics_34_18_3233.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T04:39:33Z","timestamp":1674794373000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bioinformatics\/article\/34\/18\/3233\/4980312"}},"subtitle":[],"editor":[{"given":"Janet","family":"Kelso","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2018,4,20]]},"references-count":7,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2018,9,15]]}},"URL":"https:\/\/doi.org\/10.1093\/bioinformatics\/bty321","relation":{},"ISSN":["1367-4803","1367-4811"],"issn-type":[{"value":"1367-4803","type":"print"},{"value":"1367-4811","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,9,15]]},"published":{"date-parts":[[2018,4,20]]}}}