{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:47:57Z","timestamp":1772131677330,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"19","license":[{"start":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T00:00:00Z","timestamp":1524700800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National Agency of Research and Innovation"},{"name":"Program for the Development of Basic Sciences"},{"name":"Basque Department of Industry, Tourism and Trade"},{"name":"Innovation Technology Department of Bizkaia County","award":["BFU2014-52282-P"],"award-info":[{"award-number":["BFU2014-52282-P"]}]},{"name":"Innovation Technology Department of Bizkaia County","award":["BFU2017-84653-P"],"award-info":[{"award-number":["BFU2017-84653-P"]}]},{"name":"Severo Ochoa Excellence Accreditation","award":["SEV-2016-0644"],"award-info":[{"award-number":["SEV-2016-0644"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Genes sharing functions, expression patterns or quantitative traits are not randomly distributed along eukaryotic genomes. In order to study the distribution of genes that share a given feature, we present Cluster Locator, an online analysis and visualization tool. Cluster Locator determines the number, size and position of all the clusters formed by the protein-coding genes on a list according to a given maximum gap, the percentage of gene clustering of the list and its statistical significance. The output includes a visual representation of the distribution of genes and gene clusters along the reference genome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>Cluster Locator is freely available at http:\/\/clusterlocator.bnd.edu.uy\/.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/bty336","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T19:15:06Z","timestamp":1524597306000},"page":"3377-3379","source":"Crossref","is-referenced-by-count":24,"title":["Cluster Locator, online analysis and visualization of gene clustering"],"prefix":"10.1093","volume":"34","author":[{"given":"Flavio","family":"Pazos Obreg\u00f3n","sequence":"first","affiliation":[{"name":"Developmental Neurobiology, IIBCE, Montevideo, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Soto","sequence":"additional","affiliation":[{"name":"Developmental Neurobiology, IIBCE, Montevideo, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Lav\u00edn","sequence":"additional","affiliation":[{"name":"Genome Analysis Platform, Derio, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Rosa","family":"Cort\u00e1zar","sequence":"additional","affiliation":[{"name":"Genome Analysis Platform, Derio, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Barrio","sequence":"additional","affiliation":[{"name":"Functional Genomics Unit, CIC bioGUNE, Derio, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Mar\u00eda","family":"Aransay","sequence":"additional","affiliation":[{"name":"Genome Analysis Platform, Derio, Spain"},{"name":"CIBERehd, ISCIII, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Cantera","sequence":"additional","affiliation":[{"name":"Developmental Neurobiology, IIBCE, Montevideo, Uruguay"},{"name":"Zoology Department, Stockholm University, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,4,25]]},"reference":[{"key":"2023012712493335400_bty336-B1","doi-asserted-by":"crossref","first-page":"22.","DOI":"10.1186\/1471-2105-14-22","article-title":"Kerfuffle: a web tool for multi-species gene colocalization analysis","volume":"14","author":"Aboukhalil","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"2023012712493335400_bty336-B2","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1101\/gr.211433.116","article-title":"Clustering of Drosophila housekeeping promoters facili-tates their expression","volume":"27","author":"Corrales","year":"2017","journal-title":"Genome Res"},{"key":"2023012712493335400_bty336-B3","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.ceb.2010.04.004","article-title":"Genomic neighbourhood and the regulation of gene expression","volume":"22","author":"De","year":"2010","journal-title":"Curr. 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