{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T02:00:20Z","timestamp":1775872820618,"version":"3.50.1"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,8,6]],"date-time":"2018-08-06T00:00:00Z","timestamp":1533513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"French Ministry of Research","award":["ANR-10-INBS-08"],"award-info":[{"award-number":["ANR-10-INBS-08"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>VisioProt-MS is designed to summarize and analyze intact protein and top-down proteomics data. It plots the molecular weights of eluting proteins as a function of their retention time, thereby allowing inspection of runs from liquid chromatography coupled to mass spectrometry (LC-MS). It also overlays MS\/MS identification results. VisioProt-MS is compatible with outputs from many different top-down dedicated software. To our knowledge, this is the only open source standalone application that allows the dynamic comparison of several MS files, a prerequisite for comparative analysis of different biological conditions. With its dynamic rendering, this user-friendly web application facilitates inspection, comparison and export of publication quality 2\u2009D maps from deconvoluted LC-MS run(s) and top-down proteomics data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>The Shiny-based web application VisioProt-MS is suitable for non-R users. It can be found at https:\/\/masstools.ipbs.fr\/mstools\/visioprot-ms\/ and the corresponding scripts are downloadable at https:\/\/github.com\/mlocardpaulet\/VisioProt-MS. It is governed by the CeCILL license (http:\/\/www.cecill.info).<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/bty680","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T11:11:45Z","timestamp":1533294705000},"page":"679-681","source":"Crossref","is-referenced-by-count":12,"title":["VisioProt-MS: interactive 2D maps from intact protein mass spectrometry"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2879-9224","authenticated-orcid":false,"given":"Marie","family":"Locard-Paulet","sequence":"first","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Parra","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renaud","family":"Albigot","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Mouton-Barbosa","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Bardi","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odile","family":"Burlet-Schiltz","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Marcoux","sequence":"additional","affiliation":[{"name":"Institut de Pharmacologie et de Biologie Structurale, Universit\u00e9 de Toulouse, CNRS, UPS, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,8,6]]},"reference":[{"key":"2023051511005433900_bty680-B1","doi-asserted-by":"crossref","first-page":"4231","DOI":"10.1073\/pnas.1617888114","article-title":"Identification of specific posttranslational O-mycoloylations mediating protein targeting to the mycomembrane","volume":"114","author":"Carel","year":"2017","journal-title":"Proc. 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