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Some biosynthetic pathways are encoded by enzymes collocated in the chromosome. To facilitate a more comprehensive condition and tissue-specific expression analysis of metabolic gene clusters, we developed METACLUSTER, a probabilistic framework for characterizing metabolic gene clusters using context-specific gene expression information.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>METACLUSTER is freely available at https:\/\/github.com\/mbanf\/METACLUSTER.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz021","type":"journal-article","created":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T06:33:30Z","timestamp":1547534010000},"page":"3178-3180","source":"Crossref","is-referenced-by-count":16,"title":["METACLUSTER\u2014an R package for context-specific expression analysis of metabolic gene clusters"],"prefix":"10.1093","volume":"35","author":[{"given":"Michael","family":"Banf","sequence":"first","affiliation":[{"name":"Carnegie Institution for Science Department of Plant Biology, , Stanford, CA, USA"},{"name":"EducatedGuess.ai , Siegen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kangmei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Carnegie Institution for Science Department of Plant Biology, , Stanford, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Y","family":"Rhee","sequence":"additional","affiliation":[{"name":"Carnegie Institution for Science Department of Plant Biology, , Stanford, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,1,18]]},"reference":[{"key":"2023062803480370300_btz021-B2","doi-asserted-by":"crossref","first-page":"W36","DOI":"10.1093\/nar\/gkx319","article-title":"antiSMASH 4.0\u2013improvements in chemistry prediction and gene cluster boundary identification","volume":"45","author":"Blin","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"2023062803480370300_btz021-B3","doi-asserted-by":"crossref","first-page":"E81","DOI":"10.1073\/pnas.1419547112","article-title":"Investigation of terpene diversification across multiple sequenced plant genomes","volume":"112","author":"Boutanaev","year":"2015","journal-title":"Proc. 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