{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T02:12:24Z","timestamp":1772071944471,"version":"3.50.1"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"17","license":[{"start":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T00:00:00Z","timestamp":1548374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Bioinformatics research frequently involves handling gene-centric data such as exons, transcripts, proteins and their positions relative to a reference coordinate system. The ensembldb Bioconductor package retrieves and stores Ensembl-based genetic annotations and positional information, and furthermore offers identifier conversion and coordinates mappings for gene-associated data. In support of reproducible research, data are tied to Ensembl releases and are kept separately from the software. Premade data packages are available for a variety of genomes and Ensembl releases. Three examples demonstrate typical use cases of this software.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>ensembldb is part of Bioconductor (https:\/\/bioconductor.org\/packages\/ensembldb).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz031","type":"journal-article","created":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T01:50:52Z","timestamp":1548208252000},"page":"3151-3153","source":"Crossref","is-referenced-by-count":138,"title":["ensembldb: an R package to create and use Ensembl-based annotation resources"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6977-7147","authenticated-orcid":false,"given":"Johannes","family":"Rainer","sequence":"first","affiliation":[{"name":"Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of L\u00fcbeck , Bolzano, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1520-2268","authenticated-orcid":false,"given":"Laurent","family":"Gatto","sequence":"additional","affiliation":[{"name":"de Duve Institute, UCLouvain , Brussels, Belgium"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2176-0274","authenticated-orcid":false,"given":"Christian X","family":"Weichenberger","sequence":"additional","affiliation":[{"name":"Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of L\u00fcbeck , Bolzano, Italy"}]}],"member":"286","published-online":{"date-parts":[[2019,1,25]]},"reference":[{"key":"2023062711305371100_btz031-B1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1101\/gr.1860604","article-title":"An overview of Ensembl","volume":"14","author":"Birney","year":"2004","journal-title":"Genome Res"},{"key":"2023062711305371100_btz031-B2","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/nn.2600","article-title":"Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome","volume":"13","author":"Chakrabarti","year":"2010","journal-title":"Nat. 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