{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T18:31:22Z","timestamp":1776450682339,"version":"3.51.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"20","license":[{"start":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T00:00:00Z","timestamp":1552608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Spanish Ministry of Economy"},{"name":"Industry and Competitiveness (MEIC) Plan Nacional","award":["BFU2015-63571-P"],"award-info":[{"award-number":["BFU2015-63571-P"]}]},{"name":"Centro de Excelencia Severo Ochoa"},{"name":"CERCA Programme\/Generalitat de Catalunya"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>A new version of FoldX, whose main new features allows running classic FoldX commands on structures containing RNA molecules and includes a module that allows parametrization of ligands or small molecules (ParamX) that were not previously recognized in old versions, has been released. An extended FoldX graphical user interface has also being developed (available as a python plugin for the YASARA molecular viewer) allowing user-friendly parametrization of new custom user molecules encoded using JSON format.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>http:\/\/foldxsuite.crg.eu\/<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz184","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T20:29:22Z","timestamp":1552595362000},"page":"4168-4169","source":"Crossref","is-referenced-by-count":458,"title":["FoldX 5.0: working with RNA, small molecules and a new graphical interface"],"prefix":"10.1093","volume":"35","author":[{"given":"Javier","family":"Delgado","sequence":"first","affiliation":[{"name":"Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology , Barcelona, Spain"}]},{"given":"Leandro G","family":"Radusky","sequence":"additional","affiliation":[{"name":"Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology , Barcelona, Spain"}]},{"given":"Damiano","family":"Cianferoni","sequence":"additional","affiliation":[{"name":"Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology , Barcelona, Spain"}]},{"given":"Luis","family":"Serrano","sequence":"additional","affiliation":[{"name":"Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology , Barcelona, Spain"},{"name":"Universitat Pompeu Fabra (UPF) , Barcelona, Spain"},{"name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA) , Barcelona, Spain"}]}],"member":"286","published-online":{"date-parts":[[2019,3,15]]},"reference":[{"key":"2023013108280919400_btz184-B1","doi-asserted-by":"crossref","first-page":"7422","DOI":"10.1093\/nar\/gkq683","article-title":"Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example","volume":"38","author":"Alib\u00e9s","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"2023013108280919400_btz184-B2","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0022-2836(02)00442-4","article-title":"Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations","volume":"320","author":"Guerois","year":"2002","journal-title":"J. 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