{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T21:27:10Z","timestamp":1774128430582,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"21","license":[{"start":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T00:00:00Z","timestamp":1557360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007431","name":"NRF","doi-asserted-by":"publisher","award":["NRF-2018R1A2B6008016"],"award-info":[{"award-number":["NRF-2018R1A2B6008016"]}],"id":[{"id":"10.13039\/100007431","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"publisher","award":["MOP-84287"],"award-info":[{"award-number":["MOP-84287"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"publisher","award":["PJT 159463"],"award-info":[{"award-number":["PJT 159463"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022210","name":"Canadian Statistical Sciences Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100022210","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Canadian Institutes of Health Research Strategic Training for Advanced Genetic Epidemiology","award":["GET-101831"],"award-info":[{"award-number":["GET-101831"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>For the analysis of high-throughput genomic data produced by next-generation sequencing (NGS) technologies, researchers need to identify linkage disequilibrium (LD) structure in the genome. In this work, we developed an R package gpart which provides clustering algorithms to define LD blocks or analysis units consisting of SNPs. The visualization tool in gpart can display the LD structure and gene positions for up to 20 000 SNPs in one image. The gpart functions facilitate construction of LD blocks and SNP partitions for vast amounts of genome sequencing data within reasonable time and memory limits in personal computing environments.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>The R package is available at https:\/\/bioconductor.org\/packages\/gpart.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz308","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T19:21:53Z","timestamp":1556220113000},"page":"4419-4421","source":"Crossref","is-referenced-by-count":46,"title":["gpart: human genome partitioning and visualization of high-density SNP data by identifying haplotype blocks"],"prefix":"10.1093","volume":"35","author":[{"given":"Sun Ah","family":"Kim","sequence":"first","affiliation":[{"name":"The Research Institute of Basic Sciences, Seoul National University , Seoul, South Korea"}]},{"given":"Myriam","family":"Brossard","sequence":"additional","affiliation":[{"name":"Prosserman Centre for Health Research, The Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada"}]},{"given":"Delnaz","family":"Roshandel","sequence":"additional","affiliation":[{"name":"Genetics and Genome Biology, The Hospital for Sick Children , Toronto, ON, Canada"}]},{"given":"Andrew D","family":"Paterson","sequence":"additional","affiliation":[{"name":"Genetics and Genome Biology, The Hospital for Sick Children , Toronto, ON, Canada"},{"name":"Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto , Toronto, ON, Canada"}]},{"given":"Shelley B","family":"Bull","sequence":"additional","affiliation":[{"name":"Prosserman Centre for Health Research, The Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada"},{"name":"Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto , Toronto, ON, Canada"}]},{"given":"Yun Joo","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Mathematics Education, Seoul National University , Seoul, South Korea"},{"name":"Interdisciplinary Program in Bioinformatics, Seoul National University , Seoul, South Korea"}]}],"member":"286","published-online":{"date-parts":[[2019,5,9]]},"reference":[{"key":"2023062712503521700_btz308-B1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype 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