{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:38:54Z","timestamp":1740184734899,"version":"3.37.3"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T00:00:00Z","timestamp":1573776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["CA216017","CA204120"],"award-info":[{"award-number":["CA216017","CA204120"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Bureau of Statistics of China","award":["2018LD02"],"award-info":[{"award-number":["2018LD02"]}]},{"name":"Shanghai Pujiang Program","award":["19PJ1403600"],"award-info":[{"award-number":["19PJ1403600"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>Multilayer omics profiling has become a major venue for understanding complex diseases. We develop NCutYX, an R package for clustering analysis of multilayer omics data. The package and methods jointly analyze multiple layers of omics measurements and effectively accommodate their regulations. They systematically conduct a series of analysis based on the normalized cut technique, including the clusterings of subjects and omics measurements and biclustering. The package can be valuable for its timely context, novel methods and comprehensiveness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availability and implementation<\/jats:title>\n                  <jats:p>https:\/\/cran.r-project.org\/web\/packages\/NCutYX\/.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz842","type":"journal-article","created":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T12:10:43Z","timestamp":1573647043000},"page":"1976-1977","source":"Crossref","is-referenced-by-count":0,"title":["NCutYX: a package for clustering analysis of multilayer omics data"],"prefix":"10.1093","volume":"36","author":[{"given":"Sebastian J","family":"Teran Hidalgo","sequence":"first","affiliation":[{"name":"Department of Biostatistics, Yale University , New Haven, CT 06520, USA"}]},{"given":"Mengyun","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Statistics and Management, Shanghai University of Finance and Economics , Shanghai 200433, China"}]},{"given":"Shuangge","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Yale University , New Haven, CT 06520, USA"}]}],"member":"286","published-online":{"date-parts":[[2019,11,15]]},"reference":[{"key":"2023060912013560600_btz842-B1","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.cell.2015.10.025","article-title":"The molecular taxonomy of primary prostate cancer","volume":"163","author":"Abeshouse","year":"2015","journal-title":"Cell"},{"key":"2023060912013560600_btz842-B2","doi-asserted-by":"crossref","first-page":"4386","DOI":"10.1002\/sim.7928","article-title":"Assisted gene expression-based clustering with AWNCut","volume":"37","author":"Li","year":"2018","journal-title":"Stat. 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