{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:35:00Z","timestamp":1772138100842,"version":"3.50.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T00:00:00Z","timestamp":1578441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EB027396"],"award-info":[{"award-number":["EB027396"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Gapsplit generates random samples from convex and non-convex constraint-based models by targeting under-sampled regions of the solution space. Gapsplit provides uniform coverage of linear, mixed-integer and general non-linear models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>Python and Matlab source code are freely available at http:\/\/jensenlab.net\/tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btz971","type":"journal-article","created":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T07:09:44Z","timestamp":1577948984000},"page":"2623-2625","source":"Crossref","is-referenced-by-count":13,"title":["<scp>Gapsplit<\/scp>\n                    : efficient random sampling for non-convex constraint-based models"],"prefix":"10.1093","volume":"36","author":[{"given":"Thomas C","family":"Keaty","sequence":"first","affiliation":[{"name":"Department of Bioengineering, University of Illinois at Urbana-Champaign , Urbana, IL 61801, USA"},{"name":"Carl R. 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