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Here, we first collected comprehensive information on GTs, including amino acid sequences, coding region sequences, available tertiary structures, protein classification families, catalytic reactions and metabolic pathways. Then, we developed sequence search and molecular docking processes for GTs, resulting in a GTs database (GTDB). In the present study, 520\u2009179 GTs from approximately 21\u2009647 species that involved in 394 kinds of different reactions were deposited in GTDB. GTDB has the following useful features: (i) text search is provided for retrieving the complete details of a query by combining multiple identifiers and data sources; (ii) a convenient browser allows users to browse data by different classifications and download data in batches; (iii) BLAST is offered for searching against pre-defined sequences, which can facilitate the annotation of the biological functions of query GTs; and lastly, (iv) GTdock using AutoDock Vina performs docking simulations of several GTs with the same single acceptor and displays the results based on 3Dmol.js allowing easy view of models.<\/jats:p>","DOI":"10.1093\/database\/baaa047","type":"journal-article","created":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T19:11:56Z","timestamp":1590433916000},"source":"Crossref","is-referenced-by-count":20,"title":["GTDB: an integrated resource for glycosyltransferase sequences and annotations"],"prefix":"10.1093","volume":"2020","author":[{"given":"Chenfen","family":"Zhou","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Qingwei","family":"Xu","sequence":"first","affiliation":[{"name":"College of Computer, Hubei University of Education, 129 Second Gaoxin Road, Wuhan Hi-Tech Zone, Wu Han 430205, China"}]},{"given":"Sheng","family":"He","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"},{"name":"School of Life Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong, Shanghai 201210, China"}]},{"given":"Wei","family":"Ye","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Ruifang","family":"Cao","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Pengyu","family":"Wang","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Yunchao","family":"Ling","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Xing","family":"Yan","sequence":"first","affiliation":[{"name":"CAS-Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 300 Fenglin Road, Xuhui, Shanghai 200032, China"}]},{"given":"Qingzhong","family":"Wang","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, China"}]},{"given":"Guoqing","family":"Zhang","sequence":"first","affiliation":[{"name":"National Genomics Data Center, Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Xuhui, Shanghai 200031, 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