{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:45:21Z","timestamp":1779911121709,"version":"3.53.1"},"reference-count":57,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:00:00Z","timestamp":1628812800000},"content-version":"vor","delay-in-days":224,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["5P41HD095831-03"],"award-info":[{"award-number":["5P41HD095831-03"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["ACI-1445606"],"award-info":[{"award-number":["ACI-1445606"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["ACI-1548562"],"award-info":[{"award-number":["ACI-1548562"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["ACI-1928147"],"award-info":[{"award-number":["ACI-1928147"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Echinoderm embryos and larvae are prominent experimental model systems for studying developmental mechanisms. High-quality, assembled, annotated genome sequences are now available for several echinoderm species, including representatives from most classes. The increased availability of these data necessitates the development of a nomenclature that assigns universally interpretable gene symbols to echinoderm genes to facilitate cross-species comparisons of gene functions, both within echinoderms and across other phyla. This paper describes the implementation of an improved set of echinoderm gene nomenclature guidelines that both communicates meaningful orthology information in protein-coding gene symbols and names and establishes continuity with nomenclatures developed for major vertebrate model organisms, including humans. Differences between the echinoderm gene nomenclature guidelines and vertebrate guidelines are examined and explained. This nomenclature incorporates novel solutions to allow for several types of orthologous relationships, including the single echinoderm genes with multiple vertebrate co-orthologs that result from whole-genome-duplication events. The current version of the Echinoderm Gene Nomenclature Guidelines can be found at https:\/\/www.echinobase.org\/gene\/static\/geneNomenclature.jsp<\/jats:p>\n               <jats:p>Database URL https:\/\/www.echinobase.org\/<\/jats:p>","DOI":"10.1093\/database\/baab052","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T19:12:59Z","timestamp":1627931579000},"source":"Crossref","is-referenced-by-count":6,"title":["A nomenclature for echinoderm genes"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3246-3002","authenticated-orcid":false,"given":"Thomas R","family":"Beatman","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA"},{"name":"Echinobase, #646 Mellon Institute, 4400 Fifth Ave, Pittsburgh, PA 15213, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine M","family":"Buckley","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Auburn University, 101 Rouse Life Sciences, Auburn, AL 36849, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A","family":"Cary","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica F","family":"Hinman","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA"},{"name":"Echinobase, #646 Mellon Institute, 4400 Fifth Ave, Pittsburgh, PA 15213, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles A","family":"Ettensohn","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA"},{"name":"Echinobase, #646 Mellon Institute, 4400 Fifth Ave, Pittsburgh, PA 15213, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"2021081307523610700_R1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0070-2153(03)53005-8","article-title":"4 Patterning the sea urchin embryo: gene regulatory networks, signaling pathways, and cellular interactions","volume":"53","author":"Angerer","year":"2003","journal-title":"Curr. 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