{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:24:50Z","timestamp":1771460690832,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T00:00:00Z","timestamp":1633737600000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Food Chain Safety and Environment","award":["RT 17\/5 SPECENZYM"],"award-info":[{"award-number":["RT 17\/5 SPECENZYM"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Following the European Commission No. 1332\/2008 regulation and the consequent necessity of a scientific evaluation of food enzymes (FEs) for their approval for sale on the European Union market, many FE dossiers have been submitted to the European Commission and various documents currently co-exist. In order to centralize all relevant information in one structured location that is easily accessible to support enforcement laboratories and the competent authorities, we developed a web application, called Food Enzyme Database (FEDA). FEDA allows searching and collection of information originating from many different sources in one centralized portal. Queries can be performed using key information types, which include information on the producing company, production source (strain type, genetically modified microorganism status), type of enzyme protein and evaluation status with employed evaluation criteria. The database contains all current publicly available information. Centralizing all information coupled with intuitive searching functionality also allows the generation of general statistics regarding the current market situation. FEDA is open access and is freely available at the following location: https:\/\/feda.sciensano.be.<\/jats:p>\n               <jats:p>Database URL : https:\/\/feda.sciensano.be<\/jats:p>","DOI":"10.1093\/database\/baab060","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T13:39:02Z","timestamp":1633009142000},"source":"Crossref","is-referenced-by-count":8,"title":["Food Enzyme Database (FEDA): a web application gathering information about food enzyme preparations available on the European market"],"prefix":"10.1093","volume":"2021","author":[{"given":"Marie","family":"Deckers","sequence":"first","affiliation":[{"name":"Transversal Activities in Applied Genomics (TAG), Sciensano, Brussels 1050, Belgium"},{"name":"Laboratory of Pharmaceutical Biotechnology, Ghent University, Campus Heymans, Ghent B-9000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Van Braeckel","sequence":"additional","affiliation":[{"name":"Transversal Activities in Applied Genomics (TAG), Sciensano, Brussels 1050, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Vanneste","sequence":"additional","affiliation":[{"name":"Transversal Activities in Applied Genomics (TAG), Sciensano, Brussels 1050, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Deforce","sequence":"additional","affiliation":[{"name":"Laboratory of Pharmaceutical Biotechnology, Ghent University, Campus Heymans, Ghent B-9000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Alice","family":"Fraiture","sequence":"additional","affiliation":[{"name":"Transversal Activities in Applied Genomics (TAG), Sciensano, Brussels 1050, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy h.c","family":"Roosens","sequence":"additional","affiliation":[{"name":"Transversal Activities in Applied Genomics (TAG), Sciensano, Brussels 1050, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,10,9]]},"reference":[{"key":"2021100916322321900_R1","first-page":"16","article-title":"Regulation (EC) No 1331\/2008 of the European Parliament and of the Council of 16 December 2008 establishing a common authorisation procedure for food additives, food enzymes and food flavourings","volume":"354","author":"The European Parliament and the Council of the European Union","year":"2008","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R2","first-page":"7","article-title":"Regulation (EC) No 1332\/2008 of the European Parliament and of the Council of 16 December 2008 on food enzymes and amending Council Directive 83\/417\/EEC, Council Regulation (EC) No 1493\/1999, Directive 2000\/13\/EC, Council Directive 2001\/112\/EC and(.)","volume":"51","author":"The European Parliament and the Council of the European Union","year":"2008","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R3","first-page":"16","article-title":"Regulation (EC) No 1333\/2008 of the European Parliament ans of the Council of 16 December 2998 on food additives","volume":"L 354","author":"The European Parliament and the Council of the European Union","year":"2008","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R4","first-page":"34","article-title":"Regulation (EC) No 1334\/2008 of the European Parliament and OF the Council of 16 December 2008 on flavourings and certain food ingredients with flavouring properties for use in and on foods and amending Council Regulation (EEC) No 1601\/91, Regulations (EC)","volume":"1334","author":"The European Parliament and the Council of the European Union","year":"2008","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R5","volume-title":"(EU) No 231\/2012 of 9 March 2012 laying down specifications for food additives listed in Annexes II and III to Regulation (EC) No 1333\/2008 of the European Parliament and of the Council","author":"Commission Regulation","year":"2012"},{"key":"2021100916322321900_R6","article-title":"Administrative Guidance to applicants on the suitability check of applications for authorisation of food enzymes submitted under Regulation (EC) No 1332\/2008","volume":"EN-638","author":"European Food Safety Authority","year":"2014","journal-title":"EFSA Support. Publ."},{"key":"2021100916322321900_R7","volume-title":"Food enzyme applications submitted to the Commission within the legal deadline (from 11 September 2011 to 11 March 2015)","author":"European Commission","year":"2016"},{"key":"2021100916322321900_R8","volume-title":"Bekendtg\u00f8relse om tils\u00e6tninger mv. til f\u00f8devarer 1)","year":"2020"},{"key":"2021100916322321900_R9","volume-title":"Arr\u00eat\u00e9 du 19 octobre 2006 relatif \u00e0 l\u2019emploi d\u2019auxiliaires technologiques dans la fabrication de certaines denr\u00e9es alimentaires","author":"Cerutti","year":"2006"},{"key":"2021100916322321900_R10","first-page":"1","article-title":"Guidance of the scientific panel of food contact materials, enzymes, flavourings and processing Aids (CEF) on the submission of a dossier on food enzymes for safety evaluation by the scientific panel of food contact material, enzymes, flavourings and proc","volume":"1305","author":"Anad\u00f3n","year":"2009","journal-title":"EFSA J."},{"key":"2021100916322321900_R11","first-page":"15","article-title":"Commission Regulation (EU) No 234\/2011 of 10 March 2011 implementing Regulation (EC) No 1331\/2008 of the European Parliament and of the Council establishing a common authorisation procedure for food additives, food enzymes and food flavourings","volume":"2011","author":"The European Commission","year":"2011","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R12","first-page":"21","article-title":"Commission Implementing Regulation (EU) No 562\/2012 of 27 June 2012 amending Commission Regulation (EU) No 234\/2011 with regard to specific data required for risk assessment of food enzymes","volume":"168","author":"The European Commission","year":"2012","journal-title":"Off. J. Eur. Union"},{"key":"2021100916322321900_R13","article-title":"Ad hoc meeting with industry representatives \u2013 joint dossiers on food enzymes produced from animal and plant sources","author":"European Food Safety Authority","year":"2020"},{"key":"2021100916322321900_R14","first-page":"9","article-title":"Commission Regulation (EU) No 1056\/2012 of 12 November 2012 amending Regulation (EC) No 1332\/2008 of the European Parliament and of the Council on food enzymes with regard to transitional measures","volume":"313","author":"The European Commission","year":"2012"},{"key":"2021100916322321900_R15","article-title":"Administrative guidance for the preparation of applications on food improvement agents (food enzymes, food additives and food flavourings)","volume":"18","year":"2021","journal-title":"EFSA Support. Publ."},{"key":"2021100916322321900_R16","volume-title":"EFSA Register of Questions","author":"European Food Safety Authority","year":"2010"},{"key":"2021100916322321900_R17","volume-title":"OpenEFSA portal","author":"European Food Safety Authority"},{"key":"2021100916322321900_R18","article-title":"Register of food enzymes to be considered for inclusion in","volume":"97","author":"European Commission (Directorate-general for health and food safety)","year":"2020"},{"key":"2021100916322321900_R19","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2019.125431","article-title":"Strategy for the identification of micro-organisms producing food and feed products: bacteria producing food enzymes as study case","volume":"305","author":"Deckers","year":"2020","journal-title":"Food Chem."},{"key":"2021100916322321900_R20","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2020.107295","article-title":"Screening strategy targeting the presence of food enzyme-producing fungi in food enzyme preparations","volume":"117","author":"Deckers","year":"2020","journal-title":"Food Control"}],"container-title":["Database"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/database\/article-pdf\/doi\/10.1093\/database\/baab060\/40541014\/baab060.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/database\/article-pdf\/doi\/10.1093\/database\/baab060\/40541014\/baab060.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T02:14:45Z","timestamp":1633918485000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/database\/article\/doi\/10.1093\/database\/baab060\/6385791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,1]]},"references-count":20,"URL":"https:\/\/doi.org\/10.1093\/database\/baab060","relation":{},"ISSN":["1758-0463"],"issn-type":[{"value":"1758-0463","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,10,1]]},"published":{"date-parts":[[2021,10,1]]},"article-number":"baab060"}}