{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T17:30:26Z","timestamp":1785259826289,"version":"3.55.0"},"reference-count":82,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":135,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of University and Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Large amounts of data from microbiome-related studies have been (and are currently being) deposited on international public databases. These datasets represent a valuable resource for the microbiome research community and could serve future researchers interested in integrating multiple datasets into powerful meta-analyses. However, this huge amount of data lacks harmonization and it is far from being completely exploited in its full potential to build a foundation that places microbiome research at the nexus of many subdisciplines within and beyond biology. Thus, it urges the need for data accessibility and reusability, according to findable, accessible, interoperable and reusable (FAIR) principles, as supported by National Microbiome Data Collaborative and FAIR Microbiome. To tackle the challenge of accelerating discovery and advances in skin microbiome research, we collected, integrated and organized existing microbiome data resources from human skin 16S rRNA amplicon-sequencing experiments. We generated a comprehensive collection of datasets, enriched in metadata, and organized this information into data frames ready to be integrated into microbiome research projects and advanced post-processing analyses, such as data science applications (e.g. machine learning). Furthermore, we have created a data retrieval and curation framework built on three different stages to maximize the retrieval of datasets and metadata associated with them. Lastly, we highlighted some caveats regarding metadata retrieval and suggested ways to improve future metadata submissions. Overall, our work resulted in a curated skin microbiome datasets collection accompanied by a state-of-the-art analysis of the last 10\u2009years of the skin microbiome field.<\/jats:p>\n                  <jats:p>Database URL: \u00a0https:\/\/github.com\/giuliaago\/SKIOMEMetadataRetrieval<\/jats:p>","DOI":"10.1093\/database\/baac033","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T07:07:18Z","timestamp":1652080038000},"source":"Crossref","is-referenced-by-count":10,"title":["SKIOME Project: a curated collection of skin microbiome datasets enriched with study-related metadata"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0506-8816","authenticated-orcid":false,"given":"Giulia","family":"Agostinetto","sequence":"first","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Bozzi","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"},{"name":"Department of Computational Biology, University of Lausanne, Quartier Sorge - Batiment G\u00e9nopode, Lausanne 1015, Switzerland"},{"name":"Evolutionary Genomics Group (EGG), Swiss Institute of Bioinformatics, Quartier Sorge - Batiment Amphipole, Lausanne 1015, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Porro","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"},{"name":"Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), via Fratelli Cervi, 93, Segrate (MI) 20054, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3140-3024","authenticated-orcid":false,"given":"Maurizio","family":"Casiraghi","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Labra","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1929-6652","authenticated-orcid":false,"given":"Antonia","family":"Bruno","sequence":"additional","affiliation":[{"name":"Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, Milan 20126, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"2022051614355463800_R1","doi-asserted-by":"crossref","first-page":"e00839","DOI":"10.1128\/mBio.00839-19","article-title":"New insights into the intrinsic and extrinsic factors that shape the human skin microbiome","volume":"10","author":"Dimitriu","year":"2019","journal-title":"mBio"},{"key":"2022051614355463800_R2","doi-asserted-by":"crossref","first-page":"e00695","DOI":"10.1128\/IAI.00695-20","article-title":"Living in your skin: microbes, molecules, and mechanisms","volume":"89","author":"Swaney","year":"2021","journal-title":"Infect. 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