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Despite the existence of multiple studies on PPCs, a comprehensive knowledge base that can effectively integrate and visualize the diverse risk factors associated with PPCs is currently lacking. This study aims to develop an online knowledge platform on risk factors for PPCs (Postoperative Pulmonary Complications Risk Factor Knowledge Base, PPCRKB) that categorizes and presents the risk and protective factors associated with PPCs, as well as to facilitate the development of individualized prevention and management strategies for PPCs based on the needs of each investigator. The PPCRKB is a novel knowledge base that encompasses all investigated potential risk factors linked to PPCs, offering users a web-based platform to access these risk factors. The PPCRKB contains 2673 entries, 915 risk factors that have been categorized into 11 distinct groups. These categories include habit and behavior, surgical factors, anesthetic factors, auxiliary examination, environmental factors, clinical status, medicines and treatment, demographic characteristics, psychosocial factors, genetic factors and miscellaneous factors. The PPCRKB holds significant value for PPC research. The inclusion of both quantitative and qualitative data in the PPCRKB enhances the ability to uncover new insights and solutions related to PPCs. It could provide clinicians with a more comprehensive perspective on research related to PPCs in future.<\/jats:p>\n               <jats:p>Database URL: http:\/\/sysbio.org.cn\/PPCs<\/jats:p>","DOI":"10.1093\/database\/baae054","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T15:22:40Z","timestamp":1721402560000},"source":"Crossref","is-referenced-by-count":1,"title":["PPCRKB: a risk factor knowledge base of postoperative pulmonary complications"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9126-9046","authenticated-orcid":false,"given":"Jianchao","family":"Duan","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research , West China Hospital, Sichuan University, No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Emergency Department, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College , 1 Shuai Fu Yuan, Beijing 100730, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peiyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research , West China Hospital, Sichuan University, No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Research Unit for Perioperative Stress Assessment and Clinical Decision, Chinese Academy of Medical Sciences (2018RU012), West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aibin","family":"Shao","sequence":"additional","affiliation":[{"name":"Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University , Xinchuan Road 2222, Chengdu, Sichuan 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuechao","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingyun","family":"Liu","sequence":"additional","affiliation":[{"name":"Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University , Xinchuan Road 2222, Chengdu, Sichuan 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weimin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huadong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Emergency Department, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College , 1 Shuai Fu Yuan, Beijing 100730, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, West China Hospital, Sichuan University , No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China"},{"name":"Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research , West China Hospital, Sichuan University, No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, 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