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With the advancement of sequencing technologies, reports have emerged on necrophagous insects\u2019 nuclear genomes, transcriptomes, proteomes and mitochondrial genomes. However, within the field of forensic entomology, there is currently no available database that can integrate, store and share the resources of necrophagous insects. The absence of a database poses an inconvenience to the application of entomological evidence in judicial practice and hampers the development of the forensic entomology discipline. Given this, we have developed the Home Of Forensic Entomology database, encompassing 10 core functional modules: Home, Browse, Mitochondria, Proteome, JBrowse, Search, BLAST, Tools, Case base and Maps. Notably, the \u2018Tools\u2019 module enables multiple sequence alignment analysis (Muscle), homologous protein prediction (Genewise), primer design (Primer), large-scale genomic analysis (Lastz), Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis, as well as expression profiling (PCA Analysis, Hcluster and Correlation Heatmap). In addition, the present database also works as an interactive platform for researchers by sharing forensic entomological case reports and uploading data and material. This database provides potential visitors with a comprehensive function for multi-omics data analysis, offers substantial references to researchers and criminal scene investigators and facilitates the utilization of entomological evidence in court.<\/jats:p>\n               <jats:p>Database URL: http:\/\/ihofe.com\/<\/jats:p>","DOI":"10.1093\/database\/baae058","type":"journal-article","created":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T05:01:40Z","timestamp":1720846900000},"source":"Crossref","is-referenced-by-count":1,"title":["HOFE: an interactive forensic entomological database"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7867-9189","authenticated-orcid":false,"given":"Mandie","family":"Liu","sequence":"first","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihong","family":"Qu","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9550-4193","authenticated-orcid":false,"given":"Yifei","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binta J J","family":"Jallow","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuting","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afito","family":"Luciano","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Key Laboratory of Forensic Medicine, School of Basic Medical Sciences, Xinjiang Medical University , Urumqi, Xinjiang 830017, China"},{"name":"Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases , Urumqi, Xinjiang 830017, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1443-2712","authenticated-orcid":false,"given":"Jifeng","family":"Cai","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"},{"name":"Department of Forensic Medicine, Key Laboratory of Forensic Medicine, School of Basic Medical Sciences, Xinjiang Medical University , Urumqi, Xinjiang 830017, China"},{"name":"Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases , Urumqi, Xinjiang 830017, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4763-6714","authenticated-orcid":false,"given":"Fanming","family":"Meng","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Central South University , Changsha, Hunan 410013, China"},{"name":"Department of Forensic Medicine, Key Laboratory of Forensic Medicine, School of Basic Medical Sciences, Xinjiang Medical University , Urumqi, Xinjiang 830017, China"},{"name":"Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases , Urumqi, Xinjiang 830017, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,13]]},"reference":[{"key":"2024071304534265300_R1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1146\/annurev.en.37.010192.001345","article-title":"Forensic entomology in criminal investigations","volume":"37","author":"Catts","year":"1992","journal-title":"Annu. 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